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Recombinant Mouse PCSK9/NARC1 Protein (His Tag)

Recombinant Mouse PCSK9/NARC1 Protein (His Tag)

Item no.	ELS-PKSM041128-10ug
Manufacturer	Elabscience
Amount	10 ug
Quantity options	10 ug 50 ug
Category	Oncology Neuroscience Metabolism Glucose Homeostasis Cholesterol & Lipid Metabolism Molecular Targets for Neuroscience Neural Adhesion Molecules By Cell Type Carcinoma Peptides & Proteins Recombinant Proteins Obesity Lipoprotein Receptors & Associated Proteins Cardiovascular Research Ischemia & Reperfusion Injury By Organ Bladder Cancer
Type	Proteins
Format	Liquid
Specific against	Mouse (Murine, Mus musculus)
Host	HEK293 cells
Conjugate/Tag	HIS
Purity	> 95 % as determined by reducing SDS-PAGE.
Sequence	Gln35-Gln155&Ser156-Gln694
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	FH3, HCHOLA3, NARC-1, Narc1, Neural Apoptosis-Regulated Convertase 1, PC9, Pcsk9, Proprotein Convertase 9, Proprotein Convertase Subtilisin/Kexin Type 9, Subtilisin/Kexin-Like Protease PC9
Similar products	Pcsk9, FH3, HCHOLA3, NARC-1, PC9, Proprotein Convertase Subtilisin/Kexin Type 9, Neural Apoptosis-Regulated Convertase 1, Proprotein Convertase 9, Subtilisin/Kexin-Like Protease PC9, Narc1
Shipping Condition	Cool pack
Available
Manufacturer - Category	Recombinant Proteins / Others
Manufacturer - Conjugate / Tag	C-His
Shipping Temperature	This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions	Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight	14&58.2 kDa
Observed Molecular Weight	19&60 kDa
Background	Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) is a secretory subtilase belonging to the proteinase K subfamily. PCSK9 is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the ER , the pro domain and mature chain secrete together through noncovalent interactions. PCSK9 binds with low-density lipoprotein receptor (LDLR) and plays a major regulatory role in cholesterol homeostasis.PCSK9 also plays a role in neural development.
Abbreviation	PCSK9; NARC1
Endotoxin	< 1.0 EU per μg of the protein as determined by the LAL method.
Reconstitution	Not Applicable
Formulation	Supplied as a 0.2 μm filtered solution of 50mM HEPES, 150mM NaCl, 20% Glycerol, pH 7.4.
Activity	Not validated for activity
Protein Construction	Recombinant Mouse Proprotein Convertase Subtilisin/Kexin Type 9 is produced by our Mammalian expression system and the target gene encoding Gln35-Gln155&Ser156-Gln692 is expressed with a 6His tag at the C-terminus.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

ELS-PKSM041128-10ug-datasheet.pdf

ELS-PKSM041128-10ug-safety-datasheet.pdf