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Recombinant Cynomolgus PD-L2/B7-DC/CD273 Protein (His Tag)

Recombinant Cynomolgus PD-L2/B7-DC/CD273 Protein (His Tag)

Item no.	ELS-PKSQ050026-10ug
Manufacturer	Elabscience
Amount	10 ug
Quantity options	10 ug 50 ug
Category	Oncology Metabolism Cholesterol & Lipid Metabolism By Cell Type Blastoma Carcinoma Hematology Lymphoma Peptides & Proteins Recombinant Proteins Cell Biology Cell Status Apoptosis Myelofibrosis Butyrophilins
Type	Proteins
Format	Lyophilized Powder
Specific against	Monkey (Cynomolgus, Simian)
Host	HEK293 cells
Conjugate/Tag	HIS
Purity	> 95 % as determined by reducing SDS-PAGE.
Sequence	Leu20-Pro219
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	B7-DC, B7DC, Butyrophilin B7-DC, CD273, PD-1 Ligand 2, PD-L2, PDCD1 Ligand 2, PDCD1L2, PDCD1LG2, PDL2, Programmed Cell Death 1 Ligand 2, Programmed Death Ligand 2
Similar products	PDCD1LG2, B7DC, CD273, PDCD1L2, PDL2, Butyrophilin B7-DC, PD-L2, B7-DC, Programmed Cell Death 1 Ligand 2, PD-1 Ligand 2, PDCD1 Ligand 2, Programmed Death Ligand 2
Shipping Condition	Cool pack
Available
Specificity	Cynomolgus macaques
Manufacturer - Category	Recombinant Proteins / Immune Checkpoint Proteins
Manufacturer - Conjugate / Tag	C-His
Shipping Temperature	This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight	23.4 kDa
Observed Molecular Weight	30-40 kDa
Background	Programmed Cell Death 1 Ligand 2 (PDCD1LG2) is a member of the BTN/MOG family. PDCD1LG2 contains one Ig-like C2-type domain and one Ig-like V-type domain. PDCD1LG2 is highly expressed in the heart, placenta, pancreas, lung and liver; it is weakly expressed in the spleen, lymph nodes, and thymus. PDCD1LG2 is involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PDCD1LG2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.
Abbreviation	PD-L2; B7-DC; CD273
Endotoxin	< 1.0 EU per μg of the protein as determined by the LAL method.
Reconstitution	Please refer to the printed manual for detailed information.
Formulation	Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Activity	Not validated for activity

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

ELS-PKSQ050026-10ug-datasheet.pdf

ELS-PKSQ050026-10ug-safety-datasheet.pdf