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Recombinant Macaca nemestrina PCSK9/Proprotein Convertase 9 Protein (His Tag)

Recombinant Macaca nemestrina PCSK9/Proprotein Convertase 9 Protein (His Tag)

Item no.	ELS-PKSQ050064-50ug
Manufacturer	Elabscience
Amount	50 ug
Quantity options	10 ug 50 ug
Category	Neuroscience Metabolism Glucose Homeostasis Cholesterol & Lipid Metabolism Molecular Targets for Neuroscience Peptides & Proteins Recombinant Proteins Obesity Lipoprotein Receptors & Associated Proteins
Type	Proteins
Format	Liquid
Specific against	other
Host	HEK293 cells
Conjugate/Tag	HIS
Purity	> 95 % as determined by reducing SDS-PAGE.
Sequence	Gln31-Gln152&Ser153-Gln692
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	PC9, PCSK9, Proprotein Convertase 9, Proprotein Convertase Subtilisin/Kexin Type 9, Subtilisin/Kexin-Like Protease PC9
Similar products	PCSK9, PC9, Proprotein Convertase Subtilisin/Kexin Type 9, Proprotein Convertase 9, Subtilisin/Kexin-Like Protease PC9
Shipping Condition	Cool pack
Available
Specificity	Macaca nemestrina
Manufacturer - Category	Recombinant Proteins / Others
Manufacturer - Conjugate / Tag	C-His
Shipping Temperature	This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions	Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight	14&59 kDa
Observed Molecular Weight	16-21&55-77 kDa
Background	Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) is a secretory subtilase belonging to the proteinase K subfamily. PCSK9 is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the ER , the pro domain and mature chain secrete together through noncovalent interactions. PCSK9 binds with low-density lipoprotein receptor (LDLR) and plays a major regulatory role in cholesterol homeostasis. PCSK9 also plays a role in the neural development.
Abbreviation	PCSK9; Proprotein Convertase 9
Endotoxin	< 1.0 EU per μg of the protein as determined by the LAL method.
Reconstitution	Not Applicable
Formulation	Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 0.1M Arg, 0.1M Glu, 20% glycerol, 0.01% tween20, 5% Trehalose, pH 6.0.
Activity	Not validated for activity

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

ELS-PKSQ050064-50ug-datasheet.pdf

ELS-PKSQ050064-50ug-safety-datasheet.pdf