Comparison

Human FGF R4 / CD334 Protein, His Tag European Partner

Item no. FG4-H5228-200ug
Manufacturer ACROBiosystems
Amount 200 ug
Quantity options 1 mg 200 ug
Category
Type Proteins Recombinant
Format Solid
Specific against Human (Homo sapiens)
Host HEK293
Conjugate/Tag Unconjugated, HIS
Purity 95%
Citations (1) Eswarakumar VP, et al., 2005, Cytokine Growth Factor Rev. Apr;16(2):139-49. (2) Wang J, et al., 2004, Clin Cancer Res. Sep 15;10(18 Pt 1):6169-78.
NCBI NP_002002.3
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias FGFR4,CD334,JTK2,MGC20292,TKF
Shipping Condition Room temperature
Available
Manufacturer - Category
Protein / Bio-Markers & CD Antigens
Manufacturer - Conjugate / Tag
C-6xHis, Unconjugated
Shipping Temperature
RT
Storage Conditions
-20°C
Molecular Weight
39.3 kDa
Manufacturer - Format
Powder
Description
Human FGF R4, His Tag (FG4-H5228) is expressed from human 293 cells (HEK293). It contains AA Leu 22 - Asp 369 (Accession # P22455-1).
Background
Fibroblast growth factor receptor 4(FGFR4) is also known as CD334, JTK2, hydroxyaryl-protein kinase, TKF, protein-tyrosine kinase . The FGFR4 gene provides instructions for making a protein called fibroblast growth factor receptor 4. This protein is part of a family of fibroblast growth factor receptors that share similar structures and functions. These receptor proteins play a role in important processes such as cell division, regulating cell growth and maturation, formation of blood vessels, wound healing, and embryo development.The FGFR4 protein interacts with specific growth factors to conduct signals from the environment outside the cell to the nucleus. The nucleus responds to these signals by switching on or off appropriate genes that help the cell adjust to changes in the environment. In response, the cell might divide, move, or mature to take on specialized functions. Although specific functions of FGFR4 remain unclear, studies indicate that the gene is involved in muscle development and the maturation of bone cells in the skull. The FGFR4 gene may also play a role in the development and maintenance of specialized cells (called foveal cones) in the light-sensitive layer (the retina) at the back of the eye.
Molecule
FGF R4
Exp Region
Leu 22 - Asp 369
Characteristics
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 39.3 kDa. The protein migrates as 50-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
1.0 EU per μg
Buffer
PBS, pH7.4
Stability
● -20°C to -70°C for 12 months in lyophilized state;
● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant
trehalose

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 200 ug
Available: In stock
available

Delivery expected until 7/24/2025 

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