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Human latent GDF-8 Protein, His Tag (pro & latent) (MALS verified)

Human latent GDF-8 Protein, His Tag (pro & latent) (MALS verified)

Item no.	GD8-H5243-500ug
Manufacturer	ACROBiosystems
Amount	250 ug x 2
Quantity options	250 ug x 2 50 ug
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Format	Solid
Specific against	Human (Homo sapiens)
Host	HEK293
Conjugate/Tag	Unconjugated
Purity	90%
NCBI	NP_005250.1
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	latent GDF-8,GDF-8,Myostatin,GDF8,MSTN,Growth,differentiation factor 8
Shipping Condition	Room temperature
Available
Manufacturer - Category	Protein
Manufacturer - Conjugate / Tag	N-10xHis, Unconjugated
Shipping Temperature	RT
Storage Conditions	-20°C
Molecular Weight	42.0 kDa
Manufacturer - Format	Powder
Description	Growth differentiation factor 8 (GDF8), also known as myostatin, is a unique member of the transforming growth factor-β superfamily that is expressed in human granulosa cells and has important roles in regulating a variety of ovarian functions. GDF8 acts as a negative regulator of skeletal muscle growth and differentiation. In addition to the expression in the musculoskeletal system, GDF8 is also expressed in various tissues, including the reproductive system.
Background	Growth differentiation factor 8 (GDF8), also known as myostatin, is a unique member of the transforming growth factor-β superfamily that is expressed in human granulosa cells and has important roles in regulating a variety of ovarian functions. GDF8 acts as a negative regulator of skeletal muscle growth and differentiation. In addition to the expression in the musculoskeletal system, GDF8 is also expressed in various tissues, including the reproductive system.
Molecule	GDF-8
Exp Region	Asn 24 - Ser 375
Characteristics	This protein carries a polyhistidine tag at the N-terminus. Pro-GDF8 was predominantly migrated to 45-50 kDa precursor monomers, and latent GDF8 showed 35 kDa prodomain monomer bands together with a 14 kDa growth factor monomer when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE).
Endotoxin	1.0 EU per μg
Buffer	PBS, 0.2 M Arginine, pH7.4
Stability	● -20°C to -70°C for 12 months in lyophilized state ● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant	trehalose

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

GD8-H5243-500ug-datasheet.pdf

GD8-H5243-500ug-safety-datasheet.pdf