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Human GSK-3beta / GSK-3β Protein, His Tag (active enzyme, HPLC verified)

Human GSK-3beta / GSK-3β Protein, His Tag (active enzyme, HPLC verified)

Item no.	GSB-H5545-20ug
Manufacturer	ACROBiosystems
Amount	20 ug
Quantity options	20 ug 500 ug
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Format	Liquid
Specific against	Human (Homo sapiens)
Host	Insect Cells
Conjugate/Tag	Unconjugated
Purity	90%
Dry ice	Yes
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	GSK3B,Glycogen synthase kinase-3 beta
Shipping Condition	Dry ice
Available
Manufacturer - Category	Protein
Manufacturer - Conjugate / Tag	N-10xHis, Unconjugated
Shipping Temperature	Dry ice
Storage Conditions	-70°C
Molecular Weight	48.8 kDa
Manufacturer - Format	Liquid
Description	Glycogen synthase kinase-3 (GSK-3) is a pivotal molecule in the development of Alzheimer's disease (AD). GSK-3beta is involved in the formation of paired helical filament (PHF)-tau, which is an integral component of the neurofibrillary tangle (NFT) deposits that disrupt neuronal function, and a marker of neurodegeneration in AD.
Background	Glycogen synthase kinase-3 (GSK-3) is a pivotal molecule in the development of Alzheimer's disease (AD). GSK-3beta is involved in the formation of paired helical filament (PHF)-tau, which is an integral component of the neurofibrillary tangle (NFT) deposits that disrupt neuronal function, and a marker of neurodegeneration in AD.
Molecule	GSK-3beta
Exp Region	Met 1 - Thr 420
Characteristics	This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 48.8 kDa. The protein migrates as 49-53 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin	1.0 EU per μg
Buffer	50 mM Tris, 150 mM NaCl, pH7.5
Stability	● The product MUST be stored at -70°C or lower upon receipt ● -70°C for 3 months under sterile conditions.
Protectant	glycerol

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

GSB-H5545-20ug-datasheet.pdf

GSB-H5545-20ug-safety-datasheet.pdf