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Influenza A [A/Hong Kong/483/97 (H5N1)] Hemagglutinin (HA) Protein, His Tag (MALS verified) European Partner

Item no. HA1-V5229-1mg
Manufacturer ACROBiosystems
Amount 100 ug x 10
Quantity options 100 ug 100 ug x 10
Category
Type Proteins Recombinant
Format Solid
Specific against Flu viruses (Influenza)
Host HEK293
Conjugate/Tag Unconjugated
Purity 95%
Citations (1) Suarez D.L.,et al., 1998, J. Virol. 72:6678-6688
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias HA,Hemagglutinin
Shipping Condition Room temperature
Available
Specificity Influenza
Manufacturer - Category
Protein
Manufacturer - Conjugate / Tag
C-6xHis, Unconjugated
Shipping Temperature
RT
Storage Conditions
-20°C
Molecular Weight
60.1 kDa
Manufacturer - Format
Powder
Description
Neuraminidase (NA) and hemagglutinin (HA) are major membrane glycoproteins found on the surface of influenza virus. Hemagglutinin binds to the sialic acid-containing receptors on the surface of host cells during initial infection and at the end of an infectious cycle. Hemagglutinin also plays a major role in the determination of host range restriction and virulence. As a class I viral fusion protein, hemagglutinin is responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.
Background
Neuraminidase (NA) and hemagglutinin (HA) are major membrane glycoproteins found on the surface of influenza virus. Hemagglutinin binds to the sialic acid-containing receptors on the surface of host cells during initial infection and at the end of an infectious cycle. Hemagglutinin also plays a major role in the determination of host range restriction and virulence. As a class I viral fusion protein, hemagglutinin is responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.
Molecule
Hemagglutinin/HA (Influenza Virus)
Exp Region
Asp 17 - Gln 531
Characteristics
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 60.1 kDa. The protein migrates as 67-86 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
1.0 EU per μg
Buffer
PBS, pH7.4
Stability
● -20°C to -70°C for 12 months in lyophilized state
● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant
trehalose

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug x 10
Available: In stock
available

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