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Human HLA-G&B2M&Peptide (RIIPRHLQL) Tetramer Protein (MALS verified) European Partner

Item no. HLG-H52E9-25ug
Manufacturer ACROBiosystems
Amount 25 ug
Quantity options 200 ug 25 ug
Category
Type Proteins Recombinant
Format Solid
Specific against Human (Homo sapiens)
Host HEK293
Conjugate/Tag Unconjugated, HIS
Purity 95%
NCBI NP_002118.1, NP_004039.1
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias HLA-G, HLA class I histocompatibility antigen, alpha chain G, HLAG, HLA-6.0
Shipping Condition Room temperature
Available
Manufacturer - Category
Protein / Bio-Markers & CD Antigens
Manufacturer - Conjugate / Tag
C-10xHis, Unconjugated
Shipping Temperature
RT
Storage Conditions
-20°C
Molecular Weight
36.3 kDa, 13.9 kDa and 13.3 kDa
Manufacturer - Format
Powder
Description
Human HLA-G&B2M&Peptide (RIIPRHLQL) Tetramer Protein (HLG-H52E9) is expressed from human 293 cells (HEK293). It contains AA Gly 25 - Ile 308 (HLA-G) & Ile 21 - Met 119 (B2M) & RIIPRHLQL peptide (Accession # P17693-1 (HLA-G) & P61769 (B2M) & RIIPRHLQL).
Background
Human leukocyte antigen-G (HLA-G) is a group of closely linked genes located on the short arm of human chromosome 6. Hla-g belongs to a non-classical major histocompatibility complex. MHC class I molecules are selectively highly expressed in extravvillous trophoblast cells invading the uterine decidual membrane.The gene structure of HLA-G is similar to that of HLA-A, HLA-B and HLA-C, but the termination code appears in advance so that the intracellular segment of protein product encoded by HLA-G is only 6 amino acids, which is significantly shorter than the 30 amino acids of classical HLA classI antigen. The Human HLA-G & B2M & RIIPRHLQL Complex Protein is a complex of HLA-G of the MHC Class I, B2M and RMFPNAPYL peptide.
Molecule
HLA-G & B2M & Peptide (RIIPRHLQL)
Exp Region
Gly 25 - Ile 308 (HLA-G) & Ile 21 - Met 119 (B2M) & RIIPRHLQL peptide
Characteristics
Human HLA-G&B2M&Peptide (RIIPRHLQL) Tetramer Protein is assembled by biotinylated monomer (HLM-H82E4) and streptavidin.Biotinylated Human HLA-G&B2M&Peptide (RIIPRHLQL) Complex Protein is produced by co-expression of HLA and B2M loaded with RIIPRHLQL peptide. Biotinylated Human HLA-G&B2M&Peptide (RIIPRHLQL) Complex Protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™).The protein has a calculated MW of 36.3 kDa, 13.9 kDa and 13.3 kDa. The protein migrates as 42-45 kDa and 15 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
1.0 EU per μg
Buffer
PBS, pH7.4
Stability
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant
trehalose

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 25 ug
Available: In stock
available

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