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Animal-Free APRIL/TNFSF13, Human (His)

Animal-Free APRIL/TNFSF13, Human (His)

Item no.	HY-P700016AF-2ug
Manufacturer	MedChem Express
Amount	2 ug
Quantity options	10 ug 1 ea 2 ug 50 ug
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Specific against	other
Purity	95.0
Sequence	MAVLTQKQKK QHSVLHLVPI NATSKDDSDV TEVMWQPALR RGRGLQAQGY GVRIQDAGVY LLYSQVLFQD VTFTMGQVVS REGQGRQETL FRCIRSMPSH PDRAYNSCYS AGVFHLHQGD ILSVIIPRAR AKLNLSPHGT FLGFVKL
Citations	[1]Yu G, et al. APRIL and TALL-I and receptors BCMA and TACI: system for regulating humoral immunity. Nat Immunol. 2000 Sep;1(3):252-6. [2]Nowacka KH, et al. Role of the APRIL molecule in solid tumors. Cytokine Growth Factor Rev. 2021 Oct;61:38-44. [3]Ding W, et al. APRIL knockdown suppresses migration and invasion of human colon carcinoma cells. Clin Biochem. 2009 Nov;42(16-17):1694-8. [4]Deshayes F, et al. Abnormal production of the TNF-homologue APRIL increases the proliferation of human malignant glioblastoma cell lines via a specific receptor. Oncogene. 2004 Apr 15;23(17):3005-12. [5]Hahne M, et al. APRIL, a new ligand of the tumor necrosis factor family, stimulates tumor cell growth. J Exp Med. 1998 Sep 21;188(6):1185-90.
Smiles	MAVLTQKQKK QHSVLHLVPI NATSKDDSDV TEVMWQPALR RGRGLQAQGY GVRIQDAGVY LLYSQVLFQD VTFTMGQVVS REGQGRQETL FRCIRSMPSH PDRAYNSCYS AGVFHLHQGD ILSVIIPRAR AKLNLSPHGT FLGFVKL
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Animal-Free APRIL/TNFSF13 Protein, Human (His),Human,E. coli
Shipping condition	Cool pack
Available
Manufacturer - Type	Recombinant Proteins
Shipping Temperature	Blue Ice
Storage Conditions	Stored at -20°C for 2 years
Molecular Weight	Approximately 17.29 kDa
Product Description	APRIL protein (CD256) is a ligand in the tumor necrosis factor (TNF) family that can induce proliferation, regulate tumor cell growth, and may participate in mononuclear/macrophage-mediated immune process[1]. APRIL protein is produced by myeloid cells and their precursors to accelerate cell maturation and peripheral rupture[2]. APRIL protein has been widely used in the study of lymphatic malignancies. Human APRIL protein is a type II membrane protein with cytoplasmic domain, hydrophobic transmembrane domain and extracellular domain. Animal-Free APRIL/TNFSF13 Protein, Human (His) is produced by E. coli (A105-L250) with C-terminal His-tag.This product is for cell culture use only.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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