Animal-Free BMP-3, Human (His)

Recombinant Proteins

Stored at -20°C for 2 years

BMP-3 Protein, a TGF-beta superfamily member, crucially influences early skeletal formation and acts as a bone density negative regulator. It counteracts osteogenic BMPs, hindering osteoprogenitor differentiation. BMP-3 initiates signaling via ACVR2B, activating SMAD2-dependent and SMAD-independent pathways, including TAK1 and JNK. Structurally, it forms homodimers with disulfide bonds, interacting with ACVR2B to regulate functions. Animal-Free BMP-3 Protein, Human (His) is the recombinant human-derived animal-FreeBMP-3 protein, expressed by E. coli , with C-His labeled tag. The total length of Animal-Free BMP-3 Protein, Human (His) is 110 a.a., with molecular weight of ~13.34 kDa.This product is for cell culture use only.