« Back
Home /
Animal-Free BMP-7, Human (His)

Animal-Free BMP-7, Human (His)

Item no.	HY-P700030AF-10ug
Manufacturer	MedChem Express
Amount	10 ug
Quantity options	10 ug 1 ea 2 ug 50 ug
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Specific against	other
Purity	95.0
Sequence	MANVAENSSS DQRQACKKHE LYVSFRDLGW QDWIIAPEGY AAYYCEGECA FPLNSYMNAT NHAIVQTLVH FINPETVPKP CCAPTQLNAI SVLYFDDSSN VILKKYRNMV VRACGCH
Citations	[4]Mathew S, et al. Function and effect of bone morphogenetic protein-7 in kidney bone and the bone-vascular links in chronic kidney disease. Eur J Clin Invest. 2006 Aug;36 Suppl 2:43-50. [5]Yang P, et al. The role of bone morphogenetic protein signaling in vascular calcification. Bone. 2020 Dec;141:115542. [6]Xu RH, et al. BMP4 initiates human embryonic stem cell differentiation to trophoblast. Nat Biotechnol. 2002 Dec;20(12):1261-4. [7]Beck HN, et al. Bone morphogenetic protein-5 (BMP-5) promotes dendritic growth in cultured sympathetic neurons. BMC Neurosci. 2001;2:12. [1]Sun R, et al. Expression of BMP-7 in cervical cancer and inhibition of epithelial‑mesenchymal transition by BMP-7 knockdown in HeLa cells. Int J Mol Med. 2020 May;45(5):1417-1424. [2]Miyazawa K, et al. Regulation of TGF-β Family Signaling by Inhibitory Smads. Cold Spring Harb Perspect Biol. 2017 Mar 1;9(3):a022095. [3]Dorai H, et al. Bone morphogenetic protein-7 (osteogenic protein-1) inhibits smooth muscle cell proliferation and stimulates the expression of markers that are characteristic of SMC phenotype in vitro. J Cell Physiol. 2000 Jul;184(1):37-45.
Smiles	MANVAENSSS DQRQACKKHE LYVSFRDLGW QDWIIAPEGY AAYYCEGECA FPLNSYMNAT NHAIVQTLVH FINPETVPKP CCAPTQLNAI SVLYFDDSSN VILKKYRNMV VRACGCH
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Animal-Free BMP-7 Protein, Human (His),Human,E. coli
Shipping condition	Cool pack
Available
Manufacturer - Type	Recombinant Proteins
Shipping Temperature	Blue Ice
Storage Conditions	Stored at -20°C for 2 years
Molecular Weight	Approximately 14.00 kDa
Product Description	BMP-7 protein is an important member of the TGF-β superfamily and is critical in embryogenesis, hematopoiesis, neurogenesis and bone morphogenesis. It activates canonical BMP signaling through ACVR1 and ACVR2A, phosphorylates and activates ACVR1, which in turn phosphorylates SMAD1/5/8 for target gene transcriptional regulation. Animal-Free BMP-7 Protein, Human (His) is the recombinant human-derived animal-FreeBMP-7 protein, expressed by E. coli , with C-His labeled tag. The total length of Animal-Free BMP-7 Protein, Human (His) is 117 a.a., with molecular weight of ~14.00 kDa.This product is for cell culture use only.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 10 ug

available

Request delivery time