Product Description |
IL-20 Protein, a pro-inflammatory cytokine secreted by monocytes and keratinocytes, crucially regulates immune responses, inflammation, hemopoiesis, and epidermal cell differentiation. It plays a pivotal role in tissue remodeling, wound healing, and maintaining epithelial homeostasis during infections. Additionally, it impacts actin-mediated functions in neutrophils, inhibiting phagocytosis and migration. Signaling through type I or II IL-20 receptor complexes, it activates JAK2, STAT5, AKT, and ERK1/2, forming a heterotrimeric complex with IL20RA/IL20RB. Animal-Free IL-20 Protein, Human (His) is the recombinant human-derived animal-FreeIL-20 protein, expressed by E. coli, with C-His labeled tag. The total length of Animal-Free IL-20 Protein, Human (His) is 152 a.a., with molecular weight of ~18.47 kDa. |