Product Description |
IL-30/IL-27A Proteinas, an integral Ragulator complex component, crucially senses amino acids and activates mTORC1 for cell growth regulation in response to diverse cues. Lysosomal V-ATPase and the Ragulator complex, acting as a GEF for Rag GTPases, facilitate amino acid activation. Ragulator and Rag GTPases, including LAMTOR2, recruit and activate mTORC1 on lysosomes. LAMTOR2, part of the Ragulator complex, interacts with mTORC1, Rag GTPases, and lysosomal amino acid sensor SLC38A9, contributing to growth and nutrient sensing pathways, including the lysosomal folliculin complex. Animal-Free IL-30/IL-27A Protein, Mouse (His) is the recombinant mouse-derived animal-FreeIL-30/IL-27A protein, expressed by E. coli, with C-His labeled tag. The total length of Animal-Free IL-30/IL-27A Protein, Mouse (His) is 206 a.a., with molecular weight of ~24.51 kDa. |