Product Description |
The IL-33 Protein activates NF-kappa-B and MAPK signaling, inducing Th2 cell maturation and cytokine secretion. It activates mast cells, basophils, eosinophils, and natural killer cells, enhancing macrophage polarization. It is a chemoattractant for Th2 cells, an 'alarmin' during tissue injury, and preserves Krebs cycle integrity. In quiescent endothelia, it acts as a transcriptional repressor, but is lost upon angiogenic or pro-inflammatory activation. Animal-Free IL-33 Protein, Mouse (His) is the recombinant mouse-derived animal-FreeIL-33 protein, expressed by E. coli, with C-His labeled tag. The total length of Animal-Free IL-33 Protein, Mouse (His) is 158 a.a., with molecular weight of ~18.51 kDa. |