Product Description |
IL-4, secreted by mast cells, T-cells, eosinophils, and basophils, regulates antibody production, hematopoiesis, inflammation, and T-cell responses. It induces class II MHC expression on B-cells, enhances IgE and IgG1 secretion, and regulates CD23 expression. IL-4 also influences IL31RA expression in macrophages and autophagy in dendritic cells. In addition, it affects memory and learning. IL-4 binds to IL-4R, forming type 1 or type 2 signaling complexes, activating JAK1/3 and STAT6. IL-4 modulates its effects through interactions with IL4R and IL13RA1. IL-4 Protein, Mouse (HEK293, C-His) is the recombinant mouse-derived IL-4 protein, expressed by HEK293, with C-10*His labeled tag. The total length of IL-4 Protein, Mouse (HEK293, C-His) is 120 a.a., with molecular weight of ~18 kDa. |