Product Description |
IGF-I/IGF-1 protein, structurally resembling insulin, exhibits potent growth-promoting activity. As a physiological regulator, it stimulates glucose transport and glycogen synthesis in osteoblasts, surpassing insulin's efficacy at lower concentrations. Furthermore, IGF-I contributes to synapse maturation and Ca(2+)-dependent exocytosis, crucial for olfactory bulb sensory perception. Serving as a ligand for IGF1R, it triggers tyrosine kinase activity and activates PI3K-AKT/PKB and Ras-MAPK pathways. Essential ternary complexes with integrins and IGFR1 highlight IGF-I's diverse molecular engagements. Animal-Free IGF-I/IGF-1 Protein, Mouse (His) is the recombinant mouse-derived animal-FreeIGF-I/IGF-1 protein, expressed by E. coli, with C-His labeled tag. The total length of Animal-Free IGF-I/IGF-1 Protein, Mouse (His) is 70 a.a., with molecular weight of ~8.61 kDa. |