Product Description |
CD38 Protein plays a pivotal role in cellular signaling, proficiently synthesizing cyclic ADP-ribose (cADPR) as a key second messenger for glucose-induced insulin secretion. It also facilitates the synthesis of the calcium mobilizer nicotinate-adenine dinucleotide phosphate (NAADP+). Operating at both pH 5.0 and pH 7.4, it prefers transforming 2'-phospho-cADPR into NAADP+, selectively cleaving NADP+ to cADPR and ADPRP. The multifaceted activities highlight the significance of CD38 Protein in modulating cellular responses, especially in insulin secretion and calcium mobilization. CD38 Protein, Human (HEK293, C-His) is the recombinant human-derived CD38 protein, expressed by HEK293, with C-6*His labeled tag. The total length of CD38 Protein, Human (HEK293, C-His) is 258 a.a., with molecular weight of 38-50 kDa. |