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PCSK9, Mouse (HEK293, His)

PCSK9, Mouse (HEK293, His)

Item no.	HY-P71189A-50ug
Manufacturer	MedChem Express
Amount	50 ug
Quantity options	100 ug 10 ug 20 ug 500 ug 50 ug 5 ug
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Specific against	other
Purity	96.50
Formula	Gene ID: 100102 \| Accession: Q80W65 (Q35-Q155&S156-Q694)
Sequence	QDEDGDYEEL MLALPSQEDG LADEAAHVAT ATFRRCSKEA WRLPGTYIVV LMEETQRLQI EQTAHRLQTR AARRGYVIKV LHIFYDLFPG FLVKMSSDLL GLALKLPHVE YIEEDSFVFA QSIPWNLERI IPAWHQTEED RSPDGSSQVE VYLLDTSIQG AHREIEGRVT ITDFNSVPEE DGTRFHRQAS KCDSHGTHLA GVVSGRDAGV AKGTSLHSLR VLNCQGKGTV SG
Smiles	QDEDGDYEEL MLALPSQEDG LADEAAHVAT ATFRRCSKEA WRLPGTYIVV LMEETQRLQI EQTAHRLQTR AARRGYVIKV LHIFYDLFPG FLVKMSSDLL GLALKLPHVE YIEEDSFVFA QSIPWNLERI IPAWHQTEED RSPDGSSQVE VYLLDTSIQG AHREIEGRVT ITDFNSVPEE DGTRFHRQAS KCDSHGTHLA GVVSGRDAGV AKGTSLHSLR VLNCQGKGTV SGTLIGLEFI RKSQLIQPSG PLVVLLPLAG GYSRILNAAC RHLARTGVVL VAAAGNFRDD ACLYSPASAP EVITVGATNA QDQPVTLGTL GTNFGRCVDL FAPGKDIIGA SSDCSTCFMS QSGTSQAAAH VAGIVARMLS REPTLTLAEL RQRLIHFSTK DVINMAWFPE DQQVLTPNLV ATLPPSTHET GGQLLCRTVW SAHSGPTRTA TATARCAPEE ELLSCSSFSR SGRRRGDWIE AIGGQQVCKA LNAFGGEGVY AVARCCLVPR ANCSIHNTPA ARAGLETHVH CHQKDHVLTG CSFHWEVEDL SVRRQPALRS RRQPGQCVGH QAASVYASCC HAPGLECKIK EHGISGPSEQ VTVACEAGWT LTGCNVLPGA SLTLGAYSVD NLCVARVHDT ARADRTSGEA TVAAAICCRS RPSAKASWVQ
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	PCSK9 Protein, Mouse (HEK293, His),Mouse,HEK293
Shipping condition	Cool pack
Available
Manufacturer - Type	Recombinant Proteins
Shipping Temperature	Blue Ice
Storage Conditions	Stored at -20°C for 2 years
Molecular Weight	19.37 & 55 kDa
Product Description	The PCSK9 protein regulates cholesterol levels by degrading LDLR, VLDLR, LRP1/APOER, and LRP8/APOER2 receptors. It promotes LDLR degradation, inhibits recycling, induces ubiquitination, and affects APOB degradation. Additionally, PCSK9 influences BACE1 intermediates, ENaC surface expression, and neuronal apoptosis by modulating LRP8/APOER2 levels and anti-apoptotic signaling pathways. PCSK9 Protein, Mouse (HEK293, His) is a recombinant protein dimer complex containing mouse-derived PCSK9 protein, expressed by HEK293 , with C-6*His labeled tag. PCSK9 Protein, Mouse (HEK293, His), has molecular weight of 19.37 & 55 kDa, respectively.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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HY-P71189A-50ug-safety-datasheet.pdf