Product Description |
RuvC Protein, a vital RuvA-RuvB-RuvC complex component, is crucial for processing Holliday junctions in genetic recombination and DNA repair. As an endonuclease, RuvC resolves Holliday junctions by making symmetrical single-stranded nicks, dependent on a central homology core. The consensus cleavage sequence is 5'-(A/T)TT(C>G/A)-3', with cleavage occurring on the 3'-side of the TT dinucleotide. RuvC's enzymatic activity, coupled with RuvA and RuvB, highlights its pivotal role in DNA repair and recombination. RuvC Protein, E.coli (His-SUMO) is the recombinant E. coli-derived RuvC protein, expressed by E. coli, with N-SUMO, N-6*His labeled tag. The total length of RuvC Protein, E.coli (His-SUMO) is 172 a.a., with molecular weight of ~34.6 kDa. |