Product Description |
EphA3 Protein, a receptor tyrosine kinase, exhibits promiscuous binding to membrane-bound ephrin ligands, initiating bidirectional signaling. Renowned for preferential binding to EFNA5, EphA3 activation regulates cell-cell adhesion, cytoskeletal organization, and migration. In cardiac development, likely activated by EFNA1, it controls atrioventricular canal and septum formation. In retinotectal mapping, EphA3 guides neurons, while during neuromuscular circuit development, it influences axon segregation without affecting guidance. EphA3 Protein, Human (HEK293, His) is the recombinant human-derived EphA3 protein, expressed by HEK293, with C-6*His labeled tag. The total length of EphA3 Protein, Human (HEK293, His) is 521 a.a., with molecular weight of ~67.0 kDa. |