Comparison

IRF3 Protein, Mouse (P.pastoris, Myc, His) European Partner

Manufacturer MedChem Express
Category
Type Proteins Recombinant
Specific against other
Amount 50 ug
Item no. HY-P71747-50ug
eClass 6.1 34160400
eClass 9.0 42020190
Available
Product Description
IRF3 Protein, a vital transcriptional regulator, orchestrates type I interferon-dependent immune responses against DNA and RNA viruses. In uninfected cells, it remains inactive, but viral infection triggers phosphorylation by IKBKE and TBK1 kinases, leading to conformational changes. This activates transcription of type I IFN and IFN-stimulated genes, with IRF3 transitioning from monomer to dimer form for DNA binding and nuclear localization. The cascade involves innate adapter proteins (MAVS, STING1, or TICAM1), culminating in IRF3 activation and IFN induction. IRF3 Protein, Mouse (P.pastoris, Myc, His) is the recombinant mouse-derived IRF3 protein, expressed by P. pastoris, with C-Myc, N-10*His labeled tag. The total length of IRF3 Protein, Mouse (P.pastoris, Myc, His) is 419 a.a., with molecular weight of ~50.9 kDa.
StorageTemperature
Stored at -20°C for 2 years
Shipping
Blue Ice
Molecular Weight
Approximately 50.9 kDa
Manufacturers Product type
Recombinant Proteins

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 ug
Available: In stock
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