Product Description |
TNFRSF13B Protein, the receptor for TNFSF13/APRIL and TNFSF13B/TALL1/BAFF/BLYS, exhibits high-affinity binding to both ligands. Its activation stimulates B- and T-cell function, regulating humoral immunity through calcineurin-dependent NF-AT activation, along with NF-kappa-B and AP-1 activation. TNFRSF13B binds TRAF2, TRAF5, and TRAF6, indicating involvement in diverse signaling pathways. Notably, it interacts with CAMLG's NH2-terminal domain using its C-terminus. TNFRSF13B Protein, Human (HEK293, Fc) is the recombinant human-derived TNFRSF13B protein, expressed by HEK293, with C-hFc labeled tag. The total length of TNFRSF13B Protein, Human (HEK293, Fc) is 165 a.a., with molecular weight of 50-54 kDa. |