Product Description |
S100A1, a small calcium-binding protein, is pivotal in diverse processes, including Ca(2+) homeostasis and cardiomyocyte regulation. Elevated intracellular Ca(2+) triggers S100A1 to undergo conformational changes, enabling interactions with key proteins like RYR1, RYR2, ATP2A2, and F1-ATPase in cardiomyocytes. This orchestrates sarcoplasmic reticulum Ca(2+) cycling, contributing to diastolic Ca(2+) dissociation and myofilament mechanics for enhanced relaxation. S100A1 forms dimers and engages in heterodimeric interactions with S100P, participating in various cellular processes in a calcium-dependent manner. S100A1 Protein, Human (C-His) is the recombinant human-derived S100A1 protein, expressed by E. coli, with C-6*His labeled tag. The total length of S100A1 Protein, Human (C-His) is 94 a.a., with molecular weight of ~10.03 kDa. |