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IFN-alpha 1/IFNA1 Protein, Human (P.pastoris, His) European Partner

Manufacturer MedChem Express
Category
Type Proteins Recombinant
Specific against other
Amount 20ug
Item no. HY-P73245-20ug
eClass 6.1 34160400
eClass 9.0 42020190
Available
Product Description
IFN-alpha 1 (IFNA1), belongs to type I interferon family, is produced by macrophages with antiviral activities. IFN-alpha 1 involves in the activation of JAK1 and TYK2 pathway, exerts function by inhibiting viral replication as well as modulating immune response. IFN-alpha 1/IFNA1 Protein, Human (P.pastoris, His) is produced in P.pastoris yeast cells with a C-Terminal His-tag.
StorageTemperature
Stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
Formula
Gene ID: 3439/3447 | Accession: P01562 (C24-E189)
References
[1].Zoon KC, et al. Purification and characterization of multiple components of human lymphoblastoid interferon-alpha. J Biol Chem. 1992 Jul 25; 267(21):15210-6. | [2].Zhang SY, et al. Inborn errors of interferon (IFN)-mediated immunity in humans: insights into the respective roles of IFN-alpha/beta, IFN-gamma, and IFN-lambda in host defense. Immunol Rev. 2008 Dec; 226:29-40. | [3].Gibbert K, et al. IFN-α subtypes: distinct biological activities in anti-viral therapy. Br J Pharmacol. 2013 Mar; 168(5):1048-58. | [4].De Ceuninck F, et al. IFN-α: A key therapeutic target for multiple autoimmune rheumatic diseases. Drug Discov Today. 2021 Oct; 26(10):2465-2473. | [5].Lapenta C, et al. IFN-Alpha-Mediated Differentiation of Dendritic Cells for Cancer Immunotherapy: Advances and Perspectives. Vaccines (Basel). 2020 Oct 19; 8(4):617.
MolecularWeight
Approximately 20.8 kDa

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

Amount: 20ug
Available: In stock
available

Delivery expected until 4/20/2023 

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