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IL-1RAcP/IL-1 R3, Human (HEK293, Fc)

IL-1RAcP/IL-1 R3, Human (HEK293, Fc)

Item no.	HY-P77413-100ug
Manufacturer	MedChem Express
Amount	100 ug
Quantity options	100 ug 10 ug 200 ug 50 ug 5 ug
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Specific against	other
Purity	95.0
Citations	[1]Neveu PJ, et al. Mechanisms of behavioral and neuroendocrine effects of interleukin-1 in mice. Ann N Y Acad Sci. 2000;917:175-85.\|[2]Zarezadeh Mehrabadi A, et al. The roles of interleukin-1 receptor accessory protein in certain inflammatory conditions. Immunology. 2022 May;166(1):38-46.\|[3]Wesche H, et al. The interleukin-1 receptor accessory protein (IL-1RAcP) is essential for IL-1-induced activation of interleukin-1 receptor-associated kinase (IRAK) and stress-activated protein kinases (SAP kinases). J Biol Chem. 1997 Mar 21;272(12):7727-31.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	IL-1RAcP/IL-1 R3 Protein,Human (HEK293,Fc),Human,HEK293
Shipping Condition	Cool pack
Available
Manufacturer - Type	Recombinant Proteins
Shipping Temperature	Blue Ice
Storage Conditions	Stored at -20°C for 2 years
Molecular Weight	75-85 kDa
Product Description	IL-1RAcP is a co-receptor for IL1RL2, IL1R1 and IL1RL1 in the IL-36, IL-1 and IL-33 signaling system, respectively. IL-1RAcP is an essential component of the IL-1 receptor and plays an essential role in the inflammatory process[1][2]. IL-1RAcP/IL-1 R3 Protein, Human (HEK293, Fc) is a recombinant human IL-1RAcP protein with an hFc tag at the C-terminus and is expressed in HEK293 cells. It consists of 359 amino acids (M1-E359).

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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