Comparison

LILRB4/CD85k/ILT3 Protein, Human (235a.a, HEK293, Fc) European Partner

Manufacturer MedChem Express
Category
Type Proteins Recombinant
Specific against other
Amount 50 ug
Item no. HY-P77742-50ug
eClass 6.1 34160400
eClass 9.0 42020190
Available
Product Description
LILRB4/CD85k/ILT3 Protein, a key inhibitory receptor, plays a pivotal role in immune regulation and tolerance. As a receptor for FN1, apolipoprotein APOE, and ALCAM/CD166, it inhibits receptor-mediated phosphorylation, intracellular calcium mobilization, and FCGR1A/CD64-mediated monocyte activation, reducing TNF production. It impedes T cell proliferation, induces anergy, suppresses IFNG-producing CD8+ cytotoxic T cells, promotes CD8+ T suppressor cells, up-regulates CD86 on dendritic cells, interferes with TNFRSF5-signaling, and inhibits NF-kappa-B up-regulation. Interactions with FN1 and phosphatase PTPN6 mediate these inhibitory effects. LILRB4/CD85k/ILT3 Protein, Human (HEK293, Fc) is the recombinant human-derived LILRB4/CD85k/ILT3 protein, expressed by HEK293, with C-hFc labeled tag. The total length of LILRB4/CD85k/ILT3 Protein, Human (HEK293, Fc) is 235 a.a., with molecular weight of 60-68 kDa.
StorageTemperature
Stored at -20°C for 2 years
Shipping
Blue Ice
Molecular Weight
60-68 kDa
Manufacturers Product type
Recombinant Proteins

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 ug
Available: In stock
available

Compare

Add to wishlist

Get an offer

Request delivery time

Ask a technical question

Submit a bulk request

Questions about this Product?
 
Close