Comparison

NKG2A-CD94 Heterodimer, Mouse (HEK293, mFc) European Partner

Item no. HY-P77808-20ug
Manufacturer MedChem Express
Amount 20 ug
Quantity options 100 ug 20 ug 50 ug
Category
Type Proteins Recombinant
Specific against other
Purity 95.0
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias NKG2A-CD94 Heterodimer Protein, Mouse (HEK293, mFc),Mouse,HEK293
Shipping condition Cool pack
Available
Manufacturer - Type
Recombinant Proteins
Shipping Temperature
Blue Ice
Storage Conditions
Stored at -20°C for 2 years
Molecular Weight
58-68 kDa
Product Description
NKG2A Protein, a crucial immune inhibitory receptor, forms a complex with KLRD1 on lymphocyte subsets for self-nonself discrimination. Recognizing HLA-E loaded with self-peptides, it monitors MHC class I expression in healthy cells, promoting self-tolerance. NKG2A transmits signals through ITIMs, recruiting tyrosine phosphatases to counteractivate receptors. As a key inhibitor on NK cells, it regulates their functions, distinguishing harmless from pathogenic antigens. In the tumor microenvironment, NKG2A acts as an immune inhibitory checkpoint, contributing to cell exhaustion. During viral infection, it inhibits NK cell cytotoxicity, facilitating viral immune escape. NKG2A-CD94 Heterodimer Protein, Mouse (HEK293, mFc) is a recombinant protein dimer complex containing mouse-derived NKG2A-CD94 Heterodimer protein, expressed by HEK293 , with C-mFc labeled tag. NKG2A-CD94 Heterodimer Protein, Mouse (HEK293, mFc), has molecular weight of 58-68 kDa.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 20 ug
Available: In stock
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