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IL-17RA, Human (Biotinylated, HEK293, His-Avi)

IL-17RA, Human (Biotinylated, HEK293, His-Avi)

Item no.	HY-P78161-50ug
Manufacturer	MedChem Express
Amount	50 ug
Quantity options	100 ug 20 ug 50 ug
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Specific against	other
Purity	95.0
Citations	[1]Stéphane Nesmond, et al. Characteristic Pattern of IL-17RA, IL-17RB, and IL-17RC in Monocytes/Macrophages and Mast Cells From Patients With Bullous Pemphigoid. Front Immunol. 2019 Sep 11;10:2107. [2]Xun Lin, et al. IL-17RA-signaling in Lgr5+ intestinal stem cells induces expression of transcription factor ATOH1 to promote secretory cell lineage commitment. Immunity. 2022 Feb 8;55(2):237-253.e8. [3]Laura Green, et al. Chronic Candidiasis in Children. Curr Allergy Asthma Rep. 2017 May;17(5):31. [4]Jayasri Das Sarma, et al. Functional interleukin-17 receptor A is expressed in central nervous system glia and upregulated in experimental autoimmune encephalomyelitis. J Neuroinflammation. 2009 Apr 28;6:14. [5]Erika A Rickel, et al. Identification of functional roles for both IL-17RB and IL-17RA in mediating IL-25-induced activities. J Immunol. 2008 Sep 15;181(6):4299-310.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	IL-17RA Protein, Human (Biotinylated, HEK293, His-Avi),Human,HEK293
Shipping condition	Cool pack
Available
Manufacturer - Type	Recombinant Proteins
Shipping Temperature	Blue Ice
Storage Conditions	Stored at -20°C for 2 years
Molecular Weight	60-70 kDa
Product Description	IL-17RA (Interleukin 17 receptor A), a receptor for IL-17A and IL-17F, is a type I membrane glycoprotein. It is expressed ubiquitously and exhibits a broad tissue distribution, and plays a role in many inflammatory and autoimmune diseases. IL-17RA is a common co-receptor subunit for other members of the IL-17 family. IL-17RA associates with IL-17RC to form a signaling receptor complex for IL-17A and IL-17F[1][2]. IL-17RA Protein, Human (Biotinylated, HEK293, His-Avi), a Biotinylated IL-17RA protein, is produced in HEK293 cells with a C-Terminal His-tag and a C-Terminal Avi-tag.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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