Comparison

NKG2D/CD314 Protein, Human (Biotinylated, HEK293, His-Avi) European Partner

Manufacturer MedChem Express
Category
Type Proteins Recombinant
Specific against other
Amount 50 ug
Item no. HY-P78183-50ug
eClass 6.1 34160400
eClass 9.0 42020190
Available
Product Description
NKG2D/CD314 Protein functions as a pivotal activating and costimulatory receptor in immunosurveillance, binding diverse stress-inducible ligands on tumor and virus-infected cells. It plays a dual role by stimulating NK cells and enhancing T-cell activation in CD8(+) T-cell-mediated adaptive responses. The receptor facilitates perforin-mediated elimination of ligand-expressing tumor cells, triggers calcium influx leading to TNF-alpha expression, and participates in NK cell-mediated bone marrow graft rejection. Its ligand-binding capacity extends to various MHC class I-related glycoproteins. NKG2D/CD314 forms homodimers and heterohexamers, crucial for NK cell function, and establishes disulfide-bonded heterodimers with CD94, interacting with CEACAM1 and recruiting PTPN6 for VAV1 dephosphorylation. NKG2D/CD314 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived NKG2D/CD314 protein, expressed by HEK293, with N-His, N-Avi labeled tag. The total length of NKG2D/CD314 Protein, Human (Biotinylated, HEK293, His-Avi) is 139 a.a., with molecular weight of ~19.0 kDa.
StorageTemperature
Stored at -20°C for 2 years
Shipping
Blue Ice
Molecular Weight
Approximately 19.0 kDa
Manufacturers Product type
Recombinant Proteins

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 ug
Available: In stock
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