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Human Iba1 / AIF-1 Protein, His Tag

Human Iba1 / AIF-1 Protein, His Tag

Item no.	IB1-H51H9-1mg
Manufacturer	ACROBiosystems
Amount	1 mg
Quantity options	100 ug 1 mg
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Format	Solid
Specific against	Human (Homo sapiens)
Host	E.coli
Conjugate/Tag	Unconjugated, HIS
Purity	95%
Citations	(1) Chen X, et al. 2004. Arterioscler Thromb Vasc Biol. 24(7):1217-22. (2) Kelemen SE, et al. 2005. Am J Pathol. 167(2):619-26. (3) Schulze JO, et al. 2008. FEBS J. 275(18):4627-40.
NCBI	NP_001614.3
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Iba1,AIF-1,AIF1,G1,IBA1,LCP1
Shipping Condition	Room temperature
Available
Manufacturer - Category	Protein / Other Recombinant Proteins
Manufacturer - Conjugate / Tag	C-10xHis, Unconjugated
Shipping Temperature	RT
Storage Conditions	-20°C
Molecular Weight	18.6 kDa
Manufacturer - Format	Powder
Description	Human Iba1, His Tag (IB1-H51H9) is expressed from E. coli cells. It contains AA Met 1 - Pro 147 (Accession # P55008-1).
Background	Allograft inflammatory factor 1 (AIF1), also known as IBA1, daintain and Protein G1, is an actin-binding protein. Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation.
Molecule	Iba1
Exp Region	Met 1 - Pro 147
Characteristics	This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 18.6 kDa. The protein migrates as 18-20 kDa under reducing (R) condition (SDS-PAGE).
Endotoxin	1.0 EU per μg
Buffer	PBS, pH7.4
Stability	● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant	trehalose

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

IB1-H51H9-1mg-datasheet.pdf

IB1-H51H9-1mg-safety-datasheet.pdf