Comparison

Human IFN-alpha 2b Protein, Fc Tag (MALS verified) European Partner

Item no. IFB-H5253-1mg
Manufacturer ACROBiosystems
Amount 1 mg
Quantity options 100 ug 1 mg
Category
Type Proteins Recombinant
Format Solid
Specific against Human (Homo sapiens)
Host HEK293
Conjugate/Tag Unconjugated, Fc
Purity 95%
NCBI NP_000596.2
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Shipping Condition Room temperature
Available
Manufacturer - Category
Protein / ActiveMax® Cytokines
Manufacturer - Conjugate / Tag
C-Fc, Unconjugated
Shipping Temperature
RT
Storage Conditions
-20°C
Molecular Weight
45.7 kDa
Manufacturer - Format
Powder
Description
Human IFN-alpha 2b, Fc Tag (IFB-H5253) is expressed from human 293 cells (HEK293). It contains AA Cys 24 - Glu 188 (Accession # P01563-1).
Background
IFN-alpha is a cytokine that has an immunomodulatory function. It plays an important role not only in antiviral activity but also in several physiologic functions, such as activation of dendritic cells and accelerated expression of major histocompatibility complex I and II molecules that may cause increased antigen presentation. Variants of human leukocyte interferon alpha 2 (IFN-alpha 2a, alpha 2b, and alpha 2c) differ from each other by changes in their coding regions at nucleotide positions 137 and 170. IFN-alpha 2b (IFNα-2b) is an important cytokine and used for antiviral and anticancer treatment.
Molecule
IFN-alpha 2b
Exp Region
Cys 24 - Glu 188
Characteristics
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 45.7 kDa. The protein migrates as 47-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
1.0 EU per μg
Buffer
PBS, pH7.4
Stability
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant
trehalose

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 1 mg
Available: In stock
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