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Biotinylated Mouse IgG1 Fc protein, Avitag™ (MALS verified)

Biotinylated Mouse IgG1 Fc protein, Avitag™ (MALS verified)

Item no.	IG1-M8211-25ug
Manufacturer	ACROBiosystems
Amount	25 ug
Quantity options	200 ug 25 ug
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Format	Solid
Specific against	Mouse (Murine, Mus musculus)
Host	HEK293
Conjugate/Tag	Biotin, Avi
Purity	90%
Citations	(1) Medinger M, Tzankov A,et al.( 2010), J Clin Immunol. 30 Suppl 1:S9-14.
NCBI	AAK53870.1
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	IgG1
Shipping Condition	Room temperature
Available
Manufacturer - Category	Protein / MABSol® Biotin Labeled Proteins
Manufacturer - Conjugate / Tag	C-Avi, Biotin-labeled
Shipping Temperature	RT
Storage Conditions	-20°C
Molecular Weight	27.4 kDa
Manufacturer - Format	Powder
Description	Biotinylated Mouse IgG1 Fc, Avitag (IG1-M8211) is expressed from human 293 cells (HEK293). It contains AA Val 98 - Lys 324 (Accession # AAK53870.1).
Background	Crystallizable fragments composed of the carboxy-terminal halves of both IMMUNOGLOBULIN HEAVY CHAINS linked to each other by disulfide bonds. Fc fragments contain the carboxy-terminal parts of the heavy chain constant regions that are responsible for the effector functions of an immunoglobulin (COMPLEMENT fixation, binding to the cell membrane via FC RECEPTORS, and placental transport). IgG1 Fc was reported has a novel role as a potential anti-inflammatory drug for treatment of human autoimmune diseases.
Molecule	IgG1 Fc
Exp Region	Val 98 - Lys 324
Characteristics	This protein carries an Avi tag (Avitag™) at the C-terminus. The protein has a calculated MW of 27.4 kDa. The protein migrates as 33 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin	1.0 EU per μg
Buffer	PBS, pH7.4
Stability	● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant	trehalose

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

IG1-M8211-25ug-datasheet.pdf

IG1-M8211-25ug-safety-datasheet.pdf