Comparison

Human IGFBP-7 Protein, His Tag European Partner

Item no. IG7-H5240-50ug
Manufacturer ACROBiosystems
Amount 50 ug
Quantity options 500 ug x 2 50 ug
Category
Type Proteins Recombinant
Format Solid
Specific against Human (Homo sapiens)
Host HEK293
Conjugate/Tag Unconjugated, HIS
Purity 95%
Citations (1) Yamauchi T., et al., 1994, Biochem. J. 303:591-598. (2) Oh Y., et al., 1996, J. Biol. Chem. 271:30322-30325. (3) Wilson E.M., et al., 2001, J. Clin. Endocrinol. Metab. 86:4504-4511.
NCBI NP_001544
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias IBP7,IGFBP7
Shipping Condition Room temperature
Available
Manufacturer - Category
Protein / Bio-Markers & CD Antigens
Manufacturer - Conjugate / Tag
N-6xHis, Unconjugated
Shipping Temperature
RT
Storage Conditions
-20°C
Molecular Weight
27.0 kDa
Manufacturer - Format
Powder
Description
Human IGFBP-7, His Tag (IG7-H5240) is expressed from human 293 cells (HEK293). It contains AA Asp 30 - Leu 282 (Accession # NP_001544).
Background
Insulin-like growth factor-binding protein 7 (IGFBP7) is also known as IGFBP-rP1, MAC25 protein, PGI2-stimulating factor, prostacyclin-stimulating factor and tumor-derived adhesion factor, which contains one Ig-like C2-type (immunoglobulin-like) domain, one IGFBP N-terminal domain and one Kazal-like domain. The major function of IGFBP7 is the regulation of availability of insulin-like growth factors (IGFs) in tissue as well as in modulating IGF binding to its receptors. IGFBP7 binds to IGF with high affinity except for IGF-I and IGF-II.IGFBP7 also stimulates cell adhesion. Furthermore, IGFBP7 is implicated in some cancers.
Molecule
IGFBP-7
Exp Region
Asp 30 - Leu 282
Characteristics
This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 27.0 kDa. The protein migrates as 33-35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
1.0 EU per μg
Buffer
PBS, pH7.4
Stability
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant
trehalose

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 ug
Available: In stock
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