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Human IL-1 Rrp2 / IL-1 R6 Protein, Fc Tag

Human IL-1 Rrp2 / IL-1 R6 Protein, Fc Tag

Item no.	IL2-H5254-1mg
Manufacturer	ACROBiosystems
Amount	500 ug x 2
Quantity options	100 ug 500 ug x 2
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Format	Solid
Specific against	Human (Homo sapiens)
Host	HEK293
Conjugate/Tag	Unconjugated, Fc
Purity	95%
Citations	(1) Boraschi D., et al. 2013, Semin Immunol., 25(6), 394-407. (2) Lovenberg TW., et al. 2013, Semin Immunol., 25(6), 394-407. (3) Debets R., et al. 2001, J Immunol., 167(3), 1440-6.
NCBI	NP_003845.2
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	IL-1 R6,IL-1 Rrp2,IL1RL2,IL-1RL2,IL1Rrp2,IL-1Rrp2,IL1RRP2,IL-36R
Shipping Condition	Room temperature
Available
Manufacturer - Category	Protein / Bio-Markers & CD Antigens
Manufacturer - Conjugate / Tag	C-Fc, Unconjugated
Shipping Temperature	RT
Storage Conditions	-20°C
Molecular Weight	62.4 kDa
Manufacturer - Format	Powder
Description	Human IL-1 Rrp2, Fc Tag (IL2-H5254) is expressed from human 293 cells (HEK293). It contains AA Asp 20 - Arg 335 (Accession # Q9HB29-1).
Background	The Interleukin 1 receptor family (IL-1 R) comprises at least eleven members including IL-1 RI (IL-1 R1), IL-1 RII (IL-1 R2), IL-1 RAcP (IL‑1 R3), ST2 (T1/IL-1 R4), IL-18 Ra (IL-1 Rrp/IL-1 R5), IL-1 Rrp2 (IL-1 RL2/IL-1 R6), IL-18 Rb (AcPL/IL-1 R7), IL-1RAPL‑1 (TIGIRR‑2/IL‑1 R8), and TIGIRR-1 (IL-1 R9). All family members possess three immunoglobulin (Ig)-like domains in their extracellular region. Most members also have an intracellular TIR (Toll-like receptor/IL-1 receptor signaling) domain that is also conserved in the Toll-like receptor family. Related proteins, SIGIRR (single Ig domain-containing IL-1 R-related molecule) and IL-18BP, differ from the other members by having only one Ig domain.
Molecule	IL-1 Rrp2
Exp Region	Asp 20 - Arg 335
Characteristics	This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 62.4 kDa. The protein migrates as 70-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin	1.0 EU per μg
Buffer	Tris with Glycine, Arginine and NaCl, pH7.5
Stability	● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant	trehalose

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

IL2-H5254-1mg-datasheet.pdf

IL2-H5254-1mg-safety-datasheet.pdf