Comparison

Human IL-17 RE (155-454) Protein, Fc Tag European Partner

Item no. ILE-H5256-1mg
Manufacturer ACROBiosystems
Amount 200 ug x 5
Quantity options 100 ug 200 ug x 5
Category
Type Proteins Recombinant
Format Solid
Specific against Human (Homo sapiens)
Host HEK293
Conjugate/Tag Unconjugated, Fc
Purity 95%
Citations (1) Song X. Nat Immunol. 2011. 12(12):1151-8. (2) Ramirez-Carrozzi V. Nat Immunol. 2011. 12(12):1159-66. (3) Pfeifer P. Am J Respir Cell Mol Biol. 2013. 48(4):415-21.
NCBI NP_705613.1
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias IL-17 RE,IL17RE,IL-17RE,IL-17 receptor E
Shipping Condition Room temperature
Available
Manufacturer - Category
Protein / Bio-Markers & CD Antigens
Manufacturer - Conjugate / Tag
C-Fc, Unconjugated
Shipping Temperature
RT
Storage Conditions
-20°C
Molecular Weight
60.5 kDa
Manufacturer - Format
Powder
Description
Human IL-17 RE (155-454), Fc Tag (ILE-H5256) is expressed from human 293 cells (HEK293). It contains AA Thr 155 - His 454 (Accession # Q8NFR9-1).
Background
Interleukin-17 receptor E (IL-17 RE) is an orphan receptor of the IL-17 receptor family, also known as UNQ3056, PRO9877, IL-17 Receptor E. IL-17RE is known to be expressed in the pancreas, brain, and prostate. IL-17RE is a receptor specific to IL-17C and has an essential role in host mucosal defense against infection. IL-17C functioned in a unique autocrine manner, binding to a receptor complex consisting of the receptors IL-17RA and IL-17RE, which was preferentially expressed on tissue epithelial cells. Some data identify IL-17RE as a receptor of IL-17C that regulates early innate immunity to intestinal pathogens.
Molecule
IL-17 RE
Exp Region
Thr 155 - His 454
Characteristics
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 60.5 kDa. The protein migrates as 66-80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
1.0 EU per μg
Buffer
Tris with Glycine,  Arginine and NaCl,  pH7.5
Stability
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant
trehalose

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 200 ug x 5
Available: In stock
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