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Biotinylated Human IL-11 R alpha Protein, Fc,Avitag™ (MALS verified)

Biotinylated Human IL-11 R alpha Protein, Fc,Avitag™ (MALS verified)

Manufacturer	ACROBiosystems
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Specific against	Human
Format	Powder
Amount	25ug
Item no.	ILR-H82F5-25ug
Conjugate/Tag	Precision Avi
eClass 6.1	34160400
eClass 9.0	42020190
Available
Bioactivity Legend 1	Immobilized Human IL-11, His Tag (Cat. No. IL1-H5243) at 5 μg/mL (100 μL/well) can bind Biotinylated Human IL-11 R alpha, Fc, Avitag (Cat. No. ILR-H82F5) with a linear range of 2-39 ng/mL (QC tested).
Buffer	PBS, pH7.4
Characteristics	This protein carries a human IgG1 Fc tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 66.0 kDa. The protein migrates as 90-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Description	Receptor for interleukin-11 (IL11). The receptor systems for IL6, LIF, OSM, CNTF, IL11 and CT1 can utilize IL6ST for initiating signal transmission. The IL11/IL11RA/IL6ST complex may be involved in the control of proliferation and/or differentiation of skeletogenic progenitor or other mesenchymal cells (Probable). Essential for the normal development of craniofacial bones and teeth. Restricts suture fusion and tooth number.Soluble form of IL11 receptor (sIL11RA) that acts as an agonist of IL11 activity. The IL11:sIL11RA complex binds to IL6ST/gp130 on cell surfaces and induces signaling also on cells that do not express membrane-bound IL11RA in a process called IL11 trans-signaling.
Endotoxin Level	Less than 1.0 EU per μg by the LAL method.
Exp Region	Ser 24 - Ala 370
Expression System	HEK293
Molecular Weight	66.0 kDa
Molecule	IL-11 R alpha
SDS-PAGE Legend	Biotinylated Human IL-11 R alpha, Fc, Avitag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Shipping condition	RT
Storage	-20℃

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

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Amount: 25ug

available

Delivery expected until 5/16/2024