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Human JAB1 / COPS5 Protein, Fc Tag

Human JAB1 / COPS5 Protein, Fc Tag

Item no.	JA1-H5553-1mg
Manufacturer	ACROBiosystems
Amount	1 mg
Quantity options	100 ug 1 mg
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Format	Solid
Specific against	Human (Homo sapiens)
Host	Insect Cells
Conjugate/Tag	Unconjugated, Fc
Purity	90%
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	JAB1
Shipping Condition	Room temperature
Available
Manufacturer - Category	Protein / Other Recombinant Proteins
Manufacturer - Conjugate / Tag	C-Fc, Unconjugated
Shipping Temperature	RT
Storage Conditions	-20°C
Molecular Weight	63.9 kDa
Manufacturer - Format	Powder
Description	Human JAB1 Protein, Fc Tag (JA1-H5553) is expressed from Baculovirus-Insect cells. It contains AA Ala 2 - Ser 334 (Accession # Q92905-1).
Background	Jab1, also known as CSN5, is a component of (COP9) signalosome complex (CSN) and reported to be involved in the regulation of cell proliferation, cell-cycle progression, and tumorigenesis. As a component of the COP9 signalosome complex, Jab1 could reciprocally regulate the stability and transcriptional activity of MED1 and might be a MED1 direct target gene mediating the aggressive phenotypes of HER2+tumors.
Molecule	JAB1
Exp Region	Ala 2 - Ser 334
Characteristics	This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 63.9 kDa. The protein migrates as 33 kDa and 64-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin	1.0 EU per μg
Buffer	PBS, pH7.4
Stability	● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant	trehalose

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

JA1-H5553-1mg-datasheet.pdf

JA1-H5553-1mg-safety-datasheet.pdf