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Human LBP / Lipopolysaccharide-binding (I465F) Protein, His Tag

Human LBP / Lipopolysaccharide-binding (I465F) Protein, His Tag

Item no.	LBP-H52H5-100ug
Manufacturer	ACROBiosystems
Amount	100 ug
Quantity options	100 ug 250 ug x 4
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Format	Solid
Specific against	Human (Homo sapiens)
Host	HEK293
Conjugate/Tag	Unconjugated
Purity	95%
Citations	(1) Schumann R.R., et al., 1990, Science 249:1429-1431. (2) Hubacek J.A., et al., 1997, Biochem. Biophys. Res. Commun. 236:427-430. (3) Eckert J.K., et al., 2013, Immunity 39:647-660.
NCBI	NP_004130.2 (I465F)
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Lipopolysaccharide-binding protein,LBP
Shipping Condition	Room temperature
Available
Manufacturer - Category	Protein
Manufacturer - Conjugate / Tag	C-10xHis, Unconjugated
Shipping Temperature	RT
Storage Conditions	-20°C
Molecular Weight	52.8 kDa
Manufacturer - Format	Powder
Description	Lipopolysaccharide-binding protein (LBP), a member of the BPI/LBP/Plunc superfamily, BPI/LBP family, is detected in blood serum. LBP plays a role in the innate immune response. Alao, LBP can bind to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria, and act as an affinity enhancer for CD14, facilitating its association with LPS. Furthermore, LBP is able to promote the release of cytokines in response to bacterial lipopolysaccharide.
Background	Lipopolysaccharide-binding protein (LBP), a member of the BPI/LBP/Plunc superfamily, BPI/LBP family, is detected in blood serum. LBP plays a role in the innate immune response. Alao, LBP can bind to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria, and act as an affinity enhancer for CD14, facilitating its association with LPS. Furthermore, LBP is able to promote the release of cytokines in response to bacterial lipopolysaccharide.
Molecule	Lipopolysaccharide-binding protein / LBP
Exp Region	Ala 26 - Val 481
Characteristics	This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 52.8 kDa. The protein migrates as 62 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin	1.0 EU per μg
Buffer	PBS, pH7.4
Stability	● -20°C to -70°C for 12 months in lyophilized state ● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant	trehalose

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

LBP-H52H5-100ug-datasheet.pdf

LBP-H52H5-100ug-safety-datasheet.pdf