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Human LRRC4 Protein, His Tag

Human LRRC4 Protein, His Tag

Item no.	LR4-H5221-100ug
Manufacturer	ACROBiosystems
Amount	100 ug
Quantity options	100 ug 500 ug x 2
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Format	Solid
Specific against	Human (Homo sapiens)
Host	HEK293
Conjugate/Tag	Unconjugated
Purity	90%
Citations	(1) Zhang Q., et al., 2005, FEBS Lett. 579:3674-3682. (2) Wang JR., et al., 2003, Ai Zheng 22 (9): 897-902.
NCBI	AAI11562.1
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	LRRC4,NGL-2,BAG,NAG14
Shipping Condition	Room temperature
Available
Manufacturer - Category	Protein
Manufacturer - Conjugate / Tag	C-6xHis, Unconjugated
Shipping Temperature	RT
Storage Conditions	-20°C
Molecular Weight	55.8 kDa
Manufacturer - Format	Powder
Description	LRRC4 (Leu-rich repeat/LRR-containing glycoprotein 4), LRRC4B and LRRC4C are post-synaptic adhesion molecules of the LRR protein family that induce excitatory synapse formation. LRRC4 is also known as Brain tumor-associated protein BAG, Netrin-G2 ligand (NGL-2), Nasopharyngeal carcinoma-associated gene 14 protein (NAG14), which contains 1 Ig-like (immunoglobulin-like) domain and 9 LRR (leucine-rich) repeats, 1 LRRCT domain, 1 LRRNT domain. LRRC4 / NGL-2 specifically expressed in brain. LRRC4 / NGL-2 regulates the formation of exitatory synapses through the recruitment of pre-and-postsynaptic proteins. LRRC4 / NGL-2 organize the lamina/pathway-specific differentiation of dendrites. LRRC4 / NGL-2 plays a important role for auditory synaptic responses and involved in the suppression of glioma.
Background	LRRC4 (Leu-rich repeat/LRR-containing glycoprotein 4), LRRC4B and LRRC4C are post-synaptic adhesion molecules of the LRR protein family that induce excitatory synapse formation. LRRC4 is also known as Brain tumor-associated protein BAG, Netrin-G2 ligand (NGL-2), Nasopharyngeal carcinoma-associated gene 14 protein (NAG14), which contains 1 Ig-like (immunoglobulin-like) domain and 9 LRR (leucine-rich) repeats, 1 LRRCT domain, 1 LRRNT domain. LRRC4 / NGL-2 specifically expressed in brain. LRRC4 / NGL-2 regulates the formation of exitatory synapses through the recruitment of pre-and-postsynaptic proteins. LRRC4 / NGL-2 organize the lamina/pathway-specific differentiation of dendrites. LRRC4 / NGL-2 plays a important role for auditory synaptic responses and involved in the suppression of glioma.
Molecule	LRRC4
Exp Region	Ala 39 - Lys 527
Characteristics	This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 55.8 kDa. The protein migrates as 90-110 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin	1.0 EU per μg
Buffer	PBS, pH7.4
Stability	● -20°C to -70°C for 12 months in lyophilized state ● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant	trehalose

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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LR4-H5221-100ug-datasheet.pdf

LR4-H5221-100ug-safety-datasheet.pdf