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Human HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Monomer Protein (MHC-HE446)

Human HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Monomer Protein (MHC-HE446)

Item no.	MHC-HE446-500UG
Manufacturer	KactusBio
Amount	500 ug
Quantity options	100 ug 500 ug
Category	Oncology By Cell Type Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Peptides & Proteins Recombinant Proteins Adenocarcinoma Myelofibrosis Mesothelioma Astrocytoma By Organ Heart & Blood Cancer Blastom
Type	Proteins Recombinant
Format	Liquid
Specific against	Human (Homo sapiens)
Host	E.coli
Conjugate/Tag	HIS, Avi
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Formula	Supplied as 0.22μm filtered solution in 20mM Tris, 150mM NaCl (pH 8.0).
Dry ice	Yes
Sequence	Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and SLLMWITQC peptide
NCBI	SLLMWITQC
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	MHC,MY-ESO-1,CT6.1,LAGE-2,CTAG1,CTAG1B,ESO1CTAG,LAGE2A,NY-ESO-1,CTAG1A
Shipping Condition	Dry ice
Available
Manufacturer - Type	Recombinant Protein
Manufacturer - Targets	HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC)
Manufacturer - Conjugate / Tag	C-His-Avi
Shipping Temperature	Shipped with dry ice.
Storage Conditions	Valid for 12 months from date of receipt when stored at -80°C.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Molecular Weight	The protein has a predicted MW of 35.6 kDa (HLA-A*02:01) and 11.9 kDa (B2M) same as Bis-Tris PAGE result.
Description	Recombinant Human HLA-A02:01&B2M&NY-ESO-1 (SLLMWITQC) Monomer Protein is expressed from E.coli with His tag and Avi tag at the C-Terminus.It contains Gly25-Thr305(HLA-A02:01), Ile21-Met119(B2M) and SLLMWITQC peptide.
Background	NY-ESO-1 or New York esophageal squamous cell carcinoma 1 is a well-known cancer-testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit spontaneous humoral and cellular immune responses, together with its restricted expression pattern, have rendered it a good candidate target for cancer immunotherapy.
Endotoxin	Less than 1 EU per μg by the LAL method.
Formulation	Supplied as 0.22μm filtered solution in 20mM Tris, 150mM NaCl (pH 8.0).
Biotinylated	no

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

MHC-HE446-500UG-datasheet.pdf

MHC-HE446-500UG-safety-datasheet.pdf