Comparison

Human HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Tetramer Protein (MHC-HE446T)

Item no. MHC-HE446T-100UG
Manufacturer KactusBio
Amount 100 ug
Quantity options 100 ug 500 ug
Category
Type Proteins Recombinant
Format Lyophilized
Specific against Human (Homo sapiens)
Host E.coli
Conjugate/Tag HIS, Avi
Purity > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Formula Supplied as 0.22μm filtered solution in 20mM Tris, 150mM NaCl (pH 8.0).
Sequence Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and SLLMWITQC peptide
NCBI SLLMWITQC
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias MHC,MY-ESO-1,CT6.1,LAGE-2,CTAG1,CTAG1B,ESO1CTAG,LAGE2A,NY-ESO-1,CTAG1A
Shipping Condition Room temperature
Available
Manufacturer - Type
Recombinant Protein
Manufacturer - Targets
HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC)
Manufacturer - Conjugate / Tag
C-His-Avi
Shipping Temperature
Shipped at ambient temperature.
Storage Conditions
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Molecular Weight
The protein has a predicted MW of 258 kDa. The protein migrates to 120-180 kDa (HLA-A*02:01&streptavidin tetramer) and 11.9 kDa (B2M) based on Bis-Tris PAGE result under Non reducing (N) condition.
Description
Recombinant Human HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Tetramer Protein is expressed from E.coli with His tag and Avi tag at the C-Terminus, tetramer is assembled by biotinylated monomer and streptavidin.It contains Gly25-Thr305 (HLA-A*02:01), Ile21-Met119 (B2M) and SLLMWITQC peptide.
Background
NY-ESO-1 or New York esophageal squamous cell carcinoma 1 is a well-known cancer-testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit spontaneous humoral and cellular immune responses, together with its restricted expression pattern, have rendered it a good candidate target for cancer immunotherapy.
Endotoxin
Less than 1 EU per μg by the LAL method.
Formulation
Lyophilized from 0.22 μm filtered solution in 20mM Tris, 150mM NaCl (pH 8.0). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Biotinylated
no

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug
Available: In stock
available

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