Human CD10/MME Protein (MME-HM010)

Recombinant Protein

Shipped with dry ice.

The protein has a predicted MW of 79.83 kDa. Due to glycosylation, the protein migrates to 80-100 kDa based on Bis-Tris PAGE result.

CD10 is an endopeptidase that degrades various bioactive peptides in the extracellular matrix. In addition to enzymatic degradation, it affects multiple intracellular signal transduction pathways. CD10 expression has been extensively studied in human epithelial cancers of numerous organs and sites. CD10 expression pattern depended on the histotypes of thyroid lesions. When possible metastatic tumours and non-epithelial tumours are excluded, high CD10 expression may be useful in determining whether a primary thyroid carcinoma includes an anaplastic component.

Supplied as 0.22 μm filtered solution in 50mM MES, 100mM NaCl, 10% glycerol (pH 6.5).