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Human CD10/MME Protein (MME-HM110)

Human CD10/MME Protein (MME-HM110)

Item no.	MME-HM110-100UG
Manufacturer	KactusBio
Amount	100 ug
Quantity options	100 ug 500 ug
Category	Oncology Neuroscience Aging & Neurological Disorders By Cell Type Hematology Leukemia Lymphoma Peptides & Proteins Recombinant Proteins By Organ Renal Cancer
Type	Proteins Recombinant
Format	Liquid
Specific against	Human (Homo sapiens)
Host	HEK293
Conjugate/Tag	HIS
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Formula	Lyophilized from 0.22μm filtered solution in 50mM MES, 100mM NaCl, 1mM ZnCl2, 10% Glycerol (pH 6.5). Normally 8% trehalose is added as protectant before lyophilization.
Dry ice	Yes
Sequence	Tyr52-Trp750
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Neprilysin,Atriopeptidase,Enkephalinase,NEP,Neutral,SFE,CD10,MME,CALLA,DKFZp686O16152,MGC126681,MGC126707
Shipping Condition	Dry ice
Available
Manufacturer - Type	Recombinant Protein
Manufacturer - Targets	CD10/MME
Manufacturer - Conjugate / Tag	N-His
Shipping Temperature	Shipped with dry ice.
Storage Conditions	Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Molecular Weight	The protein has a predicted MW of 80.9 kDa. Due to glycosylation, the protein migrates to 81-110 kDa based on Bis-Tris PAGE result.
Description	Recombinant Human CD10/MME Protein is expressed from HEK293 with His tag at the N-Terminus.It contains Tyr52-Trp750.
Background	CD10 is an endopeptidase that degrades various bioactive peptides in the extracellular matrix. In addition to enzymatic degradation, it affects multiple intracellular signal transduction pathways. CD10 expression has been extensively studied in human epithelial cancers of numerous organs and sites. CD10 expression pattern depended on the histotypes of thyroid lesions. When possible metastatic tumours and non-epithelial tumours are excluded, high CD10 expression may be useful in determining whether a primary thyroid carcinoma includes an anaplastic component.
Endotoxin	Less than 1 EU per μg by the LAL method.
Formulation	Supplied as 0.22μm filtered solution in 50mM MES, 100mM NaCl, 1mM ZnCl2, 10% Glycerol (pH 6.5).
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Biotinylated	no

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

MME-HM110-100UG-datasheet.pdf

MME-HM110-100UG-safety-datasheet.pdf