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Biotinylated Cynomolgus NKG2A&CD94 Protein, Fc,Avitag™ (MALS verified) European Partner

Item no. NC4-C82F7-200ug
Manufacturer ACROBiosystems
Amount 200 ug
Quantity options 200 ug 25 ug
Category
Type Proteins
Format Solid
Specific against Monkey (Cynomolgus, Simian)
Host HEK293
Conjugate/Tag Biotin, Avi, Fc
Purity 95%
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias NKG2A & CD94
Shipping Condition Room temperature
Available
Specificity Cynomolgus
Manufacturer - Category
Protein / MABSol® Biotin Labeled Proteins
Manufacturer - Conjugate / Tag
C-Fc, C-Avi, Biotin-labeled
Shipping Temperature
RT
Storage Conditions
-20°C
Molecular Weight
56.8 kDa
Manufacturer - Format
Powder
Description
Biotinylated Cynomolgus NKG2A&CD94, Fc, Avitag (NC4-C82F7) is expressed from human 293 cells (HEK293). It contains AA Ala 113 - Leu 233 (NKG2A) & Asp 57 - Ile 179 (CD94) (Accession # Q68VD2 (NKG2A) & Q68VD4 (CD94)).
Background
CD94 plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. NKG2A/CD159a is a transmembrane protein belonging to the CD94/NKG2 family of C-type lectin-like receptors that inhibits innate immune system activation. CD94 pairs with the NKG2 molecule as a heterodimer. The CD94/NKG2 complex, on the surface of natural killer cells interacts with Human Leukocyte Antigen (HLA)-E on target cells.
Molecule
NKG2A & CD94
Exp Region
Ala 113 - Leu 233 (NKG2A) & Asp 57 - Ile 179 (CD94)
Characteristics
This protein carries a human IgG1 Fc tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 56.8 kDa. The protein migrates as 65-68 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
1.0 EU per μg
Buffer
PBS, pH7.4
Stability
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant
trehalose

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 200 ug
Available: In stock
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