Comparison

Recombinant mouse Adiponectin (globular domain) protein

Item no. NKM-ADI3001-500ug
Manufacturer NKMAX
Amount 500 ug
Quantity options 100 ug 20 ug 500 ug
Category
Type Proteins Recombinant
Format Liquid
Applications SDS-PAGE
Specific against Mouse (Murine, Mus musculus)
Host E.coli
Conjugate/Tag Untagged
Purity > 95% by SDS-PAGE
Sequence MAYMYRSAFS VGLETRVTVP NVPIRFTKIF YNQQNHYDGS TGKFYCNIPG LYYFSYHITV YMKDVKVSLF KKDKAVLFTY DQYQEKNVDQ ASGSVLLHLE VGDQVWLQVY GDGDHNGLYA DNVNDSTFTG FLLYHDTN
Citations Joachim Fruebis, et al(2001) PNAS 98(4) 2005-2010
Das,K., et al(2001) Biochem. Biophys.Res.Commun. 280(4)1120-1129
Yamauchi T., et al(2001) Nature Medicine 7(8) 941-946
Berg AH, et al(2001) Nature Medicine 7(8) 947-952
Yamauchi. T., et al(2002) Nature Medicine 8(11) 1288-1295

Almer G, et al. Adiponectin-coated nanoparticles for enhanced imaging of atherosclerotic plaques. (Int J Nanomedicine. 2011){https://pubmed.ncbi.nlm.nih.gov/21753879/}
Almer G, et al. Globular domain of adiponectin: promising target molecule for detection of atherosclerotic lesions. (Biologics. 2011){https://pubmed.ncbi.nlm.nih.gov/22022204/}
Singh AK, et al. Orally active osteoanabolic agent GTDF binds to adiponectin receptors, with a preference for AdipoR1, induces adiponectin-associated signaling, and improves metabolic health in a rodent model of diabetes. (Diabetes. 2014){https://pubmed.ncbi.nlm.nih.gov/24848063/}
Khan MP, et al. Pathophysiological Mechanism of Bone Loss in Type 2 Diabetes Involves Inverse Regulation of Osteoblast Function by PGC-1α and Skeletal Muscle Atrogenes: AdipoR1 as a Potential Target for Reversing Diabetes-Induced Osteopenia. (Diabetes. 2015){https://pubmed.ncbi.nlm.nih.gov/25633418/}
Singh AK, et al. Small molecule adiponectin receptor agonist GTDF protects against skeletal muscle atrophy. (Mol Cell Endocrinol. 2017){https://pubmed.ncbi.nlm.nih.gov/27645900/}
NCBI NP_033735
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias ADIPOQ,Acdc,Acrp30,Apm1,30 kDa adipocyte complement-related protein,Adipocyte complement-related 30 kDa protein,Adipocyte C1q and collagen domain-containing protein,Adipocyte-specific protein
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Available
Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
16 kDa (138aa) confirmed by MALDI-TOF
Description
Adiponectin/Acrp30 (247amino acids) is adipocyte complement-related protein of 30kDa and exclusively expressed in differentiated adipocytes. Adiponectin (Acrp30) is a member of the complement factor C1q family and consists of signal sequence, Non-homologous sequence, collagen domain and globular domain (gAcrp30). Adiponectin (Acrp30) expression is reduced in a variety of obese and insulin-resistant states in human, monkeys and mice. Injection of Acrp30 (247aa) or gAcrp30 (globular domain) lowers serum glucose and free fatty acid level in mice. The globular domain of adiponectin/acrp30 (amino acid residues, 111-247, gAcrp30) was overexpressed in E. coli and purified by using conventional chromatography techniques.
Concentration
1mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 7.5) containing 50mM NaCl, 5mM DTT, 10% glycerol
Antigen Species
Mouse
Gene Category
Hormones & Cytokines
Domain
111-247aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Species of Protein
Mouse
Manufacturer - Search Terms
Adiponectin (globular domain), ADIPOQ, ACDC, ACRP30, APM1, GBP28, Adiponectin globular domain, Mouse, Adipocyte, C1q and collagen domain-containing protein, 30 kDa adipocyte complement-related protein, Adipocyte complement-related 30 kDa protein, ACRP30, Adipose most abunda, Adiponectin, 30 kDa adipocyte complement related protein, ACRP 30, Adipocyte C1q and collagen domain containing protein, Adipocyte complement related 30 kDa protein, Adipocyte complement related protein of 30 kDa, Adipose most abundant gene transcript 1, APM 1, GBP 28, Gelatin binding protein, ADI3001-10ug, ADI3001-20ug, ADI3001-50ug, ADI3001-100ug, ADI3001-250ug, ADI3001-500ug, ADI3001-1mg, ADI3001-10, ADI3001-20, ADI3001-50, ADI3001-100, ADI3001-250, ADI3001-500, ADI3001-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 500 ug
Available: In stock
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