Comparison

Recombinant human Dopa Decarboxylase/DDC protein

Item no. NKM-ATGP0267-20ug
Manufacturer NKMAX
Amount 20 ug
Quantity options 100 ug 20 ug 500 ug
Category
Type Proteins Recombinant
Format Liquid
Applications SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Conjugate/Tag HIS
Purity > 95% by SDS-PAGE
Sequence <MGSSHHHHHH SSGLVPRGSH TRS>MNASEFR RRGKEMVDYV ANYMEGIEGR QVYPDVEPGY LRPLIPAAAP QEPDTFEDII NDVEKIIMPG VTHWHSPYFF AYFPTASSYP AMLADMLCGA IGCIGFSWAA SPACTELETV MMDWLGKMLE LPKAFLNEKA GEGGGVIQGS ASEATLVALL AARTKVIHRL QAASPELTQA AIMEKLVAYS SDQAHSSVER AGLIGGVKLK
Citations Avgeris M., et al. (2008). Clin Biochem. 41(14-15):1140-9.
Pons R., et al. (2004). Neruology. 62(7):1058-65.

Uenishi E, et al. A novel mechanism of idiopathic orthostatic hypotension and hypocatecholaminemia due to autoimmunity against aromatic l-Amino acid decarboxylase. (Biochem Biophys Res Commun. 2024){https://pubmed.ncbi.nlm.nih.gov/38677008/}
NCBI NP_001076440.2
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias DDC,AADC,Aromatic L-amino acid decarboxylase,L-Dopa decarboxylase,Aromatic L Amino Acid Decarboxylase
Similar products DDC, Dopa Decarboxylase, AADC, Aromatic L Amino Acid Decarboxylase, Aromatic L-amino acid decarboxylase, L-Dopa decarboxylase, ATGP0267-10ug, ATGP0267-20ug, ATGP0267-50ug, ATGP0267-100ug, ATGP0267-250ug, ATGP0267-500ug, ATGP0267-1mg, ATGP0267-10, ATGP0267-20, ATGP0267-50, ATGP0267-100, ATGP0267-250, ATGP0267-500, ATGP0267-1
Available
Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
56.4 kDa (503aa) confirmed by MALDI-TOF
Description
Dopa decarboxylase, also known as DDC, is a homodimeric, pyridoxal phosphate dependent enzyme. Dopa decarboxylase is a protein implicated in 2 metabolic pathways, synthesizing 2 important neurotransmitters: dopamine and serotonin which both play key roles in many clinical disorders, including Parkinson's disease. Dopa decarboxylase is found in different areas of the brain and is particularly abundant in basal ganglia. Recombinant human Dopa decarboxylase protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Concentration
1mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 10% glycerol
Antigen Species
Human
Gene Category
Neuroscience
Domain
1-480aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Species of Protein
Human
Manufacturer - Search Terms
Dopa Decarboxylase, DDC, DDC, AADC, Aromatic L-amino acid decarboxylase, L-Dopa decarboxylase, Aromatic L Amino Acid Decarboxylase, ATGP0267-10ug, ATGP0267-20ug, ATGP0267-50ug, ATGP0267-100ug, ATGP0267-250ug, ATGP0267-500ug, ATGP0267-1mg, ATGP0267-10, ATGP0267-20, ATGP0267-50, ATGP0267-100, ATGP0267-250, ATGP0267-500, ATGP0267-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 20 ug
Available: In stock
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