Comparison

Recombinant human Aldo-keto Reductase 1C3/AKR1C3 protein

Item no. NKM-ATGP0270-20ug
Manufacturer NKMAX
Amount 20 ug
Quantity options 100 ug 20 ug 500 ug
Category
Type Proteins Recombinant
Format Liquid
Applications SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Conjugate/Tag HIS
Purity > 95% by SDS-PAGE
Sequence <MGSSHHHHHH SSGLVPRGSH> MDSKHQCVKL NDGHFMPVLG FGTYAPPEVP RSKALEVTKL AIEAGFRHID SAHLYNNEEQ VGLAIRSKIA DGSVKREDIF YTSKLWSTFH RPELVRPALE NSLKKAQLDY VDLYLIHSPM SLKPGEELSP TDENGKVIFD IVDLCTTWEA MEKCKDAGLA KSIGVSNFNR RQLEMILNKP GLKYKPVCNQ VECHPYFNRS KLLDFCKSKD
Citations Davies N., et al. (2009) Cancer Res. 69(11):4769-75
Kabututu Z., et al. (2009) J Biochem. 145(2):161-8
NCBI NP_003730.4
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Aldo-keto reductase family 1 member C3,DD3,DDX,HA1753,HAKRB,HAKRe,hluPGFS,HSD17B5,Aldo-keto reductase family 1,member C3 17 beta HSD 5(HSD17B5),AKR1 C3,Chlordecone reductase,17 beta hydroxysteroid dehydrogenase type 5,DDH1,PGFS,Prostaglandin F synthase
Similar products AKR1C3, DDX, PGFS, DD3, Chlordecone reductase, Aldo-keto reductase family 1 member C3, HA1753, HAKRB, HAKRe, HSD17B5, KIAA0119, hluPGFS, DDH1, Prostaglandin F synthase, member C3, 17 beta hydroxysteroid dehydrogenase type 5, AKR1 C3, Aldo keto reductase family 1 member C3, Aldo-keto reductase family 1, Aldo-keto Reductase1C3, member C3 17 beta HSD 5, ATGP0270-10ug, ATGP0270-20ug, ATGP0270-50ug, ATGP0270-100ug, ATGP0270-250ug, ATGP0270-500ug, ATGP0270-1mg, ATGP0270-10, ATGP0270-20, ATGP0270-50, ATGP0270-100, ATGP0270-250, ATGP0270-500, ATGP0270-1
Available
Manufacturer - Type
Recombinant Protein
Manufacturer - Applications
SDS-PAGE, Enzyme Activity
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
39 kDa (343aa) confirmed by MALDI-TOF
Description
AKR1C3, also known as PGFS, is a member of the aldo-keto reductase superfamily which catalyzes the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9 alpha, 11 beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and differentiation. Recombinant human AKR1C3 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
1mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol
Antigen Species
Human
Gene Category
Redox Proteins
Domain
1-323aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment Only
Specific activity is > 1, 000pmol/min/ug, and is defined as the amount of enzyme that catalyze the oxidation of 1.0pmole 1-Acenaphthenol in the presence of NADP per minute at pH 8.8 at 25C.
Species of Protein
Human
Manufacturer - Search Terms
Aldo-keto Reductase1C3, AKR1C3, Aldo-keto reductase family 1 member C3, Aldo-keto reductase family 1, member C3, DD3, DDX, HA1753, HAKRB, HAKRe, hluPGFS, HSD17B5, KIAA0119, Aldo-keto reductase family 1, member C3 17 beta HSD 5, AKR1 C3, Chlordecone reductase, 17 beta hydroxysteroid dehydrogenase type 5, Aldo keto reductase family 1 member C3, DDH1, HAKRe, HSD17B5, PGFS, Prostaglandin F synthase, ATGP0270-10ug, ATGP0270-20ug, ATGP0270-50ug, ATGP0270-100ug, ATGP0270-250ug, ATGP0270-500ug, ATGP0270-1mg, ATGP0270-10, ATGP0270-20, ATGP0270-50, ATGP0270-100, ATGP0270-250, ATGP0270-500, ATGP0270-1
Manufacturer - Alternative Names
Aldo-keto reductase family 1 member C3, DD3, DDX, HA1753, HAKRB, HAKRe, hluPGFS, HSD17B5, Aldo-keto reductase family 1, member C3 17 beta HSD 5(HSD17B5), AKR1 C3, Chlordecone reductase, 17 beta hydroxysteroid dehydrogenase type 5, DDH1, PGFS, Prostaglandin F synthase

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 20 ug
Available: In stock
available

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