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Recombinant human GRB2 protein

Recombinant human GRB2 protein

Item no.	NKM-ATGP0286-20ug
Manufacturer	NKMAX
Amount	20 ug
Quantity options	100 ug 20 ug 500 ug
Category	Oncology Neuroscience Neural Signaling By Cell Type Blastoma Carcinoma Glioma Hematology Lymphoma Myeloma Melanoma Sarcoma Peptides & Proteins Recombinant Proteins Cell Biology Cell Culture Cytokines Adenocarcinoma SDS-PAGE Astrocytoma By Organ Bladder Cancer
Type	Proteins Recombinant
Format	Liquid
Applications	SDS-PAGE
Specific against	Human (Homo sapiens)
Host	E.coli
Conjugate/Tag	HIS
Purity	> 95% by SDS-PAGE
Sequence	<MGSSHHHHHH SSGLVPRGSH> MEAIAKYDFK ATADDELSFK RGDILKVLNE ECDQNWYKAE LNGKDGFIPK NYIEMKPHPW FFGKIPRAKA EEMLSKQRHD GAFLIRESES APGDFSLSVK FGNDVQHFKV LRDGAGKYFL WVVKFNSLNE LVDYHRSTSV SRNQQIFLRD IEQVPQQPTY VQALFDFDPQ EDGELGFRRG DFIHVMDNSD PNWWKGACHG QTGMFPRNYV
Citations	Rudd CE., et al. (2009) Immunol Rev. 229(1):12-26. Weisswange I., et al. (2009) Nature. 458(7234):87-91.
NCBI	NP_002077.1
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Growth factor receptor-bound protein 2 isoform 1,Growth factor receptor-bound protein 2 isoform 1,ASH,EGFRBP-GRB2,GRB3-3,Growth factor receptor-bound protein 2 isoform 1 Abundant SRC homology,Adapter protein GRB2,Ash protein,EGFRBP GRB2,Epidermal growth factor receptor binding protein,Epidermal growth factor receptor binding protein GRB2,GRB 2,GRB2 adapter protein,Grb3 3,Growth factor receptor bound protein 2,Growth factor receptor bound protein 3,HT027,MST084,MSTP084,OTTHuMP00000166096,OTTHuMP00000166097,OTTHuMP00000166098,Protein ASH,SEM5,SH2/SH3 adapter GRB2.
Similar products	GRB2, ASH, EGFRBP-GRB2, MST084, MSTP084, HT027, Adapter protein GRB2, Ash protein, EGFRBP GRB2, Epidermal growth factor receptor binding protein, Epidermal growth factor receptor binding protein GRB2, GRB 2, GRB2 adapter protein, Grb3 3, Growth factor receptor bound protein 2, Growth factor receptor bound protein 3, SEM5, Growth factor receptor-bound protein 2 isoform 1, GRB3-3, Growth factor receptor-bound protein 2 isoform 1 Abundant SRC homology, OTTHuMP00000166096, OTTHuMP00000166097, OTTHuMP00000166098, Protein ASH, SH2/SH3 adapter GRB2., ATGP0286-10ug, ATGP0286-20ug, ATGP0286-50ug, ATGP0286-100ug, ATGP0286-250ug, ATGP0286-500ug, ATGP0286-1mg, ATGP0286-10, ATGP0286-20, ATGP0286-50, ATGP0286-100, ATGP0286-250, ATGP0286-500, ATGP0286-1
Available
Manufacturer - Type	Recombinant Protein
Storage Conditions	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight	27 kDa (237aa) confirmed by MALDI-TOF
Description	Growth factor receptor-bound protein 2 also known as Grb2 is an adaptor protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. GRB2 is widely expressed and also binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Grb2 is composed of an SH2 domain flanked on each side by an SH3 domain. Inhibition of Grb2 function impairs developmental processes in various organisms and blocks transformation and proliferation of various cell types. Recombinant human GRB2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Concentration	1mg/ml (determined by Bradford assay)
Formulation	Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 30% glycerol
Antigen Species	Human
Gene Category	Signal Transduction
Domain	1-217aa
Species of Protein	Human
Manufacturer - Search Terms	GRB2, Growth factor receptor-bound protein 2 isoform 1, Growth factor receptor-bound protein 2 isoform 1, ASH, EGFRBP-GRB2, GRB3-3, Growth factor receptor-bound protein 2 isoform 1 Abundant SRC homology, Adapter protein GRB2, Ash protein, EGFRBP GRB2, Epidermal growth factor receptor binding protein, Epidermal growth factor receptor binding protein GRB2, GRB 2, GRB2 adapter protein, Grb3 3, Growth factor receptor bound protein 2, Growth factor receptor bound protein 3, HT027, MST084, MSTP084, OTTHuMP00000166096, OTTHuMP00000166097, OTTHuMP00000166098, Protein ASH, SEM5, SH2/SH3 adapter GRB2., ATGP0286-10ug, ATGP0286-20ug, ATGP0286-50ug, ATGP0286-100ug, ATGP0286-250ug, ATGP0286-500ug, ATGP0286-1mg, ATGP0286-10, ATGP0286-20, ATGP0286-50, ATGP0286-100, ATGP0286-250, ATGP0286-500, ATGP0286-1
Manufacturer - Alternative Names	Growth factor receptor-bound protein 2 isoform 1, Growth factor receptor-bound protein 2 isoform 1, ASH, EGFRBP-GRB2, GRB3-3, Growth factor receptor-bound protein 2 isoform 1 Abundant SRC homology, Adapter protein GRB2, Ash protein, EGFRBP GRB2, Epidermal growth factor receptor binding protein, Epidermal growth factor receptor binding protein GRB2, GRB 2, GRB2 adapter protein, Grb3 3, Growth factor receptor bound protein 2, Growth factor receptor bound protein 3, HT027, MST084, MSTP084, OTTHuMP00000166096, OTTHuMP00000166097, OTTHuMP00000166098, Protein ASH, SEM5, SH2/SH3 adapter GRB2.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 20 ug

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Delivery expected until 7/31/2025

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