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Recombinant human Annexin A1/ANXA1 protein

Recombinant human Annexin A1/ANXA1 protein

Item no.	NKM-ATGP0291-20ug
Manufacturer	NKMAX
Amount	20 ug
Quantity options	100 ug 20 ug 4 ug
Category	Oncology Neuroscience Neuroinflammation By Cell Type Carcinoma Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Format	Liquid
Applications	SDS-PAGE
Specific against	Human (Homo sapiens)
Host	E.coli
Conjugate/Tag	Untagged
Purity	> 90% by SDS-PAGE
Sequence	MAMVSEFLKQ AWFIENEEQE YVQTVKSSKG GPGSAVSPYP TFNPSSDVAA LHKAIMVKGV DEATIIDILT KRNNAQRQQI KAAYLQETGK PLDETLKKAL TGHLEEVVLA LLKTPAQFDA DELRAAMKGL GTDEDTLIEI LASRTNKEIR DINRVYREEL KRDLAKDITS DTSGDFRNAL LSLAKGDRSE DFGVNEDLAD SDARALYEAG ERRKGTDVNV FNTILTTRSY PQ
Citations	Lim LH., et al. (2007). FASEB J. 21(4):968-75 Kovacic RT., et al. (1991). Biochemistry. 30(37):9015-21 Jung SH, et al. Integrative proteomic profiling of protein activity and interactions using protein arrays. (Mol Cell Proteomics. 2012){https://pubmed.ncbi.nlm.nih.gov/22843993/} Jung SH, et al. Identification of transglutaminase 2 kinase substrates using a novel on-chip activity assay. (Biosens Bioelectron. 2016){https://pubmed.ncbi.nlm.nih.gov/27040940/} Jung SH, et al. Systematic investigation of protein kinase A substrate proteins using on-chip protein kinase kinetic profiling. (Analyst. 2017){https://pubmed.ncbi.nlm.nih.gov/28536714/} Vais H, et al. ER-luminal [Ca2+] regulation of InsP3 receptor gating mediated by an ER-luminal peripheral Ca2+-binding protein. (Elife. 2020){https://pubmed.ncbi.nlm.nih.gov/32420875/}
NCBI	NP_000691.1
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Annexin I,Annexin-1,Calpactin II,Calpactin-2,Chromobindin-9,Lipocortin I,phospholipase A2 inhibitory protein,p35,Annexin Ac2-26,ANX1,LPC1
Similar products	Annexin I, ANXA1, p35, Annexin A1, ANX1, LPC1, Lipocortin I, Calpactin II, Chromobindin-9, Phospholipase A2 inhibitory protein, Annexin 1, AnnexinA1, Annexin-1, Calpactin-2, AnnexinI, Annexin1, ANX 1, ANX A1, ANXA 1, ANXA1 protein, Calpactin 2, CalpactinII, Chromobindin 9, Chromobindin9, HGNC:533, Lipocortin 1, Lipocortin1, LipocortinI, LPC 1, LPC-1, Lipocortin-I, Lipocortin-1, Calpactin-II, Calpactin2, Annexin-I, Annexin Ac2-26, Annexin Ac2 26, ATGP0291-10ug, ATGP0291-20ug, ATGP0291-50ug, ATGP0291-100ug, ATGP0291-250ug, ATGP0291-500ug, ATGP0291-1mg, ATGP0291-010, ATGP0291-020, ATGP0291-050, ATGP0291-100, ATGP0291-250, ATGP0291-500, ATGP0291-01M
Available
Manufacturer - Type	Recombinant Protein
Storage Conditions	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight	38.7 kDa (346aa) confirmed by MALDI-TOF
Description	Annexin A1, also known as Lipocortin I, belongs to a family of Ca (2+) -dependent phospholipid binding proteins that are preferentially located on the cytosolic face of the plasma membrane. It promotes membrane fusion and is also involved in exocytosis. Since Annexin A1 has phospholipase A2 inhibitory activity to bind from two to four calcium ions with high affinity, this protein may have potential anti-inflammatory activity. The detection of this protein by immunocytochemical means reportedly provides a simple, highly sensitive and specific assay for diagnosis of hairy cell leukemia. Recombinant human Annexin A1 protein was expressed in E. coli and purified by using conventional chromatography.
Concentration	1mg/ml (determined by Bradford assay)
Formulation	Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 100mM NaCl, 1mM DTT, 10% glycerol,
Antigen Species	Human
Gene Category	Serology
Domain	1-346aa
Species of Protein	Human
Manufacturer - Search Terms	Phospholipase A2 inhibitory protein, p35, LPC-1, LPC1, LPC 1, Lipocortin-I, LipocortinI, Lipocortin-1, Lipocortin1, Lipocortin I, Lipocortin 1, HGNC:533, Chromobindin-9, Chromobindin9, Chromobindin 9, Calpactin-II, CalpactinII, Calpactin-2, Calpactin2, Calpactin II, Calpactin 2, ANXA1 protein, ANXA1, ANXA 1, ANX1, ANX A1, ANX 1, Annexin-I, AnnexinI, AnnexinA1, Annexin-1, Annexin1, Annexin I, Annexin Ac2-26, Annexin Ac2 26, Annexin A1, Annexin 1, ATGP0291-10ug, ATGP0291-20ug, ATGP0291-50ug, ATGP0291-100ug, ATGP0291-250ug, ATGP0291-500ug, ATGP0291-1mg, ATGP0291-010, ATGP0291-020, ATGP0291-050, ATGP0291-100, ATGP0291-250, ATGP0291-500, ATGP0291-01M

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 20 ug

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Delivery expected until 7/31/2025

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