Comparison

Recombinant human Aldo-keto Reductase 1B10/AKR1B10 protein

Item no. NKM-ATGP0314-100ug
Manufacturer NKMAX
Amount 100 ug
Quantity options 100 ug 20 ug 500 ug
Category
Type Proteins Recombinant
Format Liquid
Applications SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Conjugate/Tag Untagged
Purity > 95% by SDS-PAGE
Sequence MATFVELSTK AKMPIVGLGT WKSPLGKVKE AVKVAIDAGY RHIDCAYVYQ NEHEVGEAIQ EKIQEKAVKR EDLFIVSKLW PTFFERPLVR KAFEKTLKDL KLSYLDVYLI HWPQGFKSGD DLFPKDDKGN AIGGKATFLD AWEAMEELVD EGLVKALGVS NFSHFQIEKL LNKPGLKYKP VTNQVECHPY LTQEKLIQYC HSKGITVTAY SPLGSPDRPW AKPEDPSLLE DP
Citations Yabe D., et al. (1997) J Biol Chem. 272(29):18232-9.
Vorum H., et al. (1998) Biochim Biophys Acta. 1386(1):121-31.
NCBI NP_064695
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Aldo-keto reductase family 1 member B10,AKR1B11,AKR1B12,ALDRLn,ARL-1,ARL1,HIS,AKR1B10,Aldose reductase like,Aldose reductase related protein,ARL 1,hARP,SI reductase,Small intestine reductase
Similar products ARL1, AKR1B10, HIS, AKR1B11, ALDRLn, AKR1B12, Small intestine reductase, ARL-1, SI reductase, Aldo-keto reductase family 1 member B10, member B10, Aldose reductase like, Aldose reductase related protein, ARL 1, hARP, Aldo-keto reductase family 1, Aldo-keto Reductase1B10, member B10 Aldose reductase like, ATGP0314-10ug, ATGP0314-20ug, ATGP0314-50ug, ATGP0314-100ug, ATGP0314-250ug, ATGP0314-500ug, ATGP0314-1mg, ATGP0314-010, ATGP0314-020, ATGP0314-050, ATGP0314-100, ATGP0314-250, ATGP0314-500, ATGP0314-01M
Available
Manufacturer - Type
Recombinant Protein
Manufacturer - Applications
SDS-PAGE, Enzyme Activity
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
36 kDa (316aa) confirmed by MALDI-TOF
Description
AKR1B10, also known as Aldo-keto reductase family 1, member B10, AKR1B10 is a monomeric protein that efficiently catalyzes the reduction of aromatic and aliphatic aldehydes and ketones. AKR1B10 is ubiquitously expressed in many human tissues but is highly expressed in small intestine, colon and adrenal gland. This protein is pathogenically involved in diabetic complications and has been reported that AKR1B10 is overexpressed in human tumors, such as liver, breast, and lung cancer, and may play a critical role in the development and progression of cancer. Recombinant human AKR1B10 protein was expressed in E. coli and purified by using conventional chromatography.
Concentration
1mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol
Antigen Species
Human
Gene Category
Redox Proteins
Domain
1-316aa
Bioactivity Comment Only
Specific activity is > 1, 500pmol/min/ug, and was obtained by measuring the decrease of NADP in absorbance at 340nm resulting from NADPH at pH 7.0 at 37C.
Species of Protein
Human
Manufacturer - Search Terms
AKR1B10, AKR1B11, AKR1B12, Aldo-keto reductase family 1, Aldo-keto reductase family 1 member B10, Aldo-keto Reductase1B10, Aldose reductase like, Aldose reductase related protein, ALDRLn, ARL 1, ARL1, ARL-1, hARP, HIS, member B10, member B10 Aldose reductase like, SI reductase, Small intestine reductase, ATGP0314-10ug, ATGP0314-20ug, ATGP0314-50ug, ATGP0314-100ug, ATGP0314-250ug, ATGP0314-500ug, ATGP0314-1mg, ATGP0314-010, ATGP0314-020, ATGP0314-050, ATGP0314-100, ATGP0314-250, ATGP0314-500, ATGP0314-01M

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug
Available: In stock
available

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